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1. WO2022212289 - MUTANT HERPESVIRUS AND VACCINE COMPOSITIONS

Publication Number WO/2022/212289
Publication Date 06.10.2022
International Application No. PCT/US2022/022211
International Filing Date 28.03.2022
IPC
A61K 35/763 2015.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
76Viruses; Subviral particles; Bacteriophages
763Herpes virus
A61K 39/245 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
C07K 14/035 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
01DNA viruses
03Herpetoviridae, e.g. pseudorabies virus
035Herpes simplex virus I or II
CPC
A61K 39/245
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2710/16621
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16611Simplexvirus, e.g. human herpesvirus 1, 2
16621Viruses as such, e.g. new isolates, mutants or their genomic sequences
C12N 2710/16622
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16611Simplexvirus, e.g. human herpesvirus 1, 2
16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
C12N 2710/16634
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16611Simplexvirus, e.g. human herpesvirus 1, 2
16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
Applicants
  • RATIONAL VACCINES, INC. [US]/[US]
  • FERNANDEZ, Agustin [US]/[US]
  • GERSHBURG, Edward [US]/[US]
Inventors
  • FERNANDEZ, Agustin
  • GERSHBURG, Edward
  • PREDKI, Paul
Agents
  • LAHERTY, Carol
  • CHRISTIANSEN II, William T.
  • TEAGUE, Lawrence J.
Priority Data
63/167,38829.03.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MUTANT HERPESVIRUS AND VACCINE COMPOSITIONS
(FR) HERPÈSVIRUS MUTANT ET COMPOSITIONS DE VACCIN
Abstract
(EN) Compositions and methods related to a mutant herpesvirus and a mutant ICPO protein. Vaccine compositions comprising the mutant herpesvirus and/or mutant ICPO protein. Methods of treatment using the mutant herpesvirus and/or mutant ICPO protein.
(FR) L'invention concerne des compositions et des méthodes associées à un herpèsvirus mutant et à une protéine ICP0 mutante. L'invention concerne également des compositions de vaccin comprenant l'herpèsvirus mutant et/ou la protéine ICP0 mutante. L'invention concerne, en outre, des méthodes de traitement faisant appel à l'herpèsvirus mutant et/ou à la protéine ICP0 mutante.
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