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1. WO2022208279 - COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES

Publication Number WO/2022/208279
Publication Date 06.10.2022
International Application No. PCT/IB2022/052798
International Filing Date 28.03.2022
IPC
A61B 17/072 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
03for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
068Surgical staplers
072for applying a row of staples in a single action
A61B 17/064 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
03for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
064Surgical staples
A61B 17/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
A61B 90/00 2016.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/-A61B50/171
CPC
A61B 17/0644
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
064Surgical staples, ; i.e. penetrating the tissue
0644penetrating the tissue, deformable to closed position
A61B 17/0686
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
068Surgical staplers ; , e.g. containing multiple staples or clamps
0682for applying U-shaped staples or clamps, e.g. without a forming anvil
0686having a forming anvil staying below the tissue during stapling
A61B 17/072
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
068Surgical staplers ; , e.g. containing multiple staples or clamps
072for applying a row of staples in a single action ; , e.g. the staples being applied simultaneously
A61B 17/07292
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
068Surgical staplers ; , e.g. containing multiple staples or clamps
072for applying a row of staples in a single action ; , e.g. the staples being applied simultaneously
07292Reinforcements for staple line, e.g. pledgets
A61B 2017/00004
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00004(bio)absorbable, (bio)resorbable, resorptive
A61B 2017/00526
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00526Methods of manufacturing
Applicants
  • CILAG GMBH INTERNATIONAL [CH]/[CH]
Inventors
  • SHELTON, IV, Frederick E.
  • HARRIS, Jason L.
  • VENDELY, Michael J.
Agents
  • TUNSTALL, Christopher Stephen
  • BETTRIDGE, Paul Sebastian
  • BRUNNER, John Michael Owen
  • SMALL, Gary James
Priority Data
17/216,97830.03.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES
(FR) ADJUVANTS COMPRESSIBLES À CARACTÉRISTIQUES DE LIBÉRATION DE MÉDICAMENT
Abstract
(EN) Compressible adjuncts for use with a surgical cartridge are provided. In one exemplary embodiment, a compressible adjunct includes a biocompatible adjunct material that is configured to be releasably retained on a staple cartridge and that is configured to be delivered to tissue by deployment of staples in the cartridge. The adjunct material includes a hollow lattice macrostructure having at least one drug contained therein. The hollow lattice macrostructure is formed of a plurality of unit cells having at least one absorbable sub-structure that is formed in the plurality of unit cells. The at least one absorbable sub-structure is configured to control a rate of fluid movement through the respective unit cell so as to control the release of the at least one drug from the adjunct material when the adjunct material is in a tissue deployed state. Stapling assemblies for use with a surgical stapler are also provided.
(FR) L'invention concerne des adjuvants compressibles destinés à être utilisés avec une cartouche chirurgicale. Dans un mode de réalisation donné à titre d'exemple, un adjuvant compressible comprend un matériau adjuvant biocompatible qui est conçu pour être retenu amovible sur une cartouche d'agrafes et qui est conçu pour être administré au tissu par le déploiement d'agrafes dans la cartouche. Le matériau adjuvant comprend une macrostructure en treillis creuse ayant au moins un médicament contenu dans celle-ci. La macrostructure en treillis creuse est formée d'une pluralité de cellules unitaires ayant au moins une sous-structure absorbable qui est formée dans la pluralité de cellules unitaires. Ladite sous-structure absorbable est conçue pour réguler une vitesse de déplacement de fluide à travers la cellule unitaire respective de sorte à réguler la libération dudit médicament à partir du matériau adjuvant lorsque le matériau adjuvant se trouve dans un état déployé de tissu. L'invention concerne également des ensembles d'agrafage destinés à être utilisés avec une agrafeuse chirurgicale.
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