Feedback
Settings

Settings

Goto Application

1. WO2022165427 - COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS

Submit observation
PermaLink
Publication Number WO/2022/165427
Publication Date 04.08.2022
International Application No. PCT/US2022/014757
International Filing Date 01.02.2022
IPC
A61K 31/138 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
135having aromatic rings, e.g. methadone
138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61P 27/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
C07C 217/84 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
217Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
78having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
80having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
82of the same non-condensed six-membered aromatic ring
84the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
CPC
A61K 31/137
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine ; or methadone
A61P 27/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
C07B 59/001
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
59Introduction of isotopes of elements into organic compounds ; ; Labelled organic compounds per se
001Acyclic or carbocyclic compounds
C07C 217/72
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
217Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
54having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
64with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
66with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
72linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
C07C 2601/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
2601Systems containing only non-condensed rings
12with a six-membered ring
14The ring being saturated
C07C 2601/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
2601Systems containing only non-condensed rings
12with a six-membered ring
16the ring being unsaturated
Applicants
  • CASE WESTERN RESERVE UNIVERSITY [US]/[US]
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors
  • TOCHTROP, Gregory
  • KISER, Philip
  • ZHANG, Jianye
  • PALCZEWSKI, Krzysztof
Agents
  • SUTKUS, Richard A.
Priority Data
63/144,24201.02.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS
(FR) COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DE TROUBLES OCULAIRES
front page image
Abstract
(EN) A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, tautomer, or solvate thereof.
(FR) Une méthode de traitement d'un trouble oculaire chez un sujet en ayant besoin comprend l'administration au sujet d'une quantité thérapeutiquement efficace d'un composé de formule (I) ou d'un sel, tautomère ou solvate pharmaceutiquement acceptable associé.
Latest bibliographic data on file with the International Bureau
# -