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1. WO2022165247 - DETECTING THE PRESENCE OR ABSENCE OF MULTIPLE TYPES OF CANCER

Publication Number WO/2022/165247
Publication Date 04.08.2022
International Application No. PCT/US2022/014408
International Filing Date 28.01.2022
IPC
C12Q 1/6886 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/154
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
154Methylation markers
C12Q 2600/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
16Primer sets for multiplex assays
G01N 2440/12
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2440Post-translational modifications [PTMs] in chemical analysis of biological material
12alkylation, e.g. methylation, (iso-)prenylation, farnesylation
G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
G01N 33/57473
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57473involving carcinoembryonic antigen, i.e. CEA
Applicants
  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH [US]/[US]
  • EXACT SCIENCES CORPORATION [US]/[US]
Inventors
  • KISIEL, John B.
  • MAHONEY, Douglas W.
  • TAYLOR, William R.
  • ALLAWI, Hatim T.
  • KATEROV, Viatcheslav E.
  • AHLQUIST (DECEASED), David A.
Agents
  • GOETZ, Robert A.
Priority Data
63/143,61129.01.2021US
63/278,88912.11.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DETECTING THE PRESENCE OR ABSENCE OF MULTIPLE TYPES OF CANCER
(FR) DÉTECTION DE LA PRÉSENCE OU DE L'ABSENCE DE MULTIPLES TYPES DE CANCER
Abstract
(EN) Provided herein is technology for screening multiple types of cancer from a biological sample, and particularly, but not exclusively, to methods, compositions, and related uses for simultaneously detecting the presence of multiple types of cancer (e.g., liver cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, gastric cancer, bladder cancer, breast cancer, cervical cancer, colorectal cancer, prostate cancer, renal cancer, and uterine cancer) from a biological sample (e.g., stool sample, tissue sample, organ secretion sample, CSF sample, saliva sample, blood sample, plasma sample or urine sample).
(FR) L'invention concerne une technologie de criblage de multiples types de cancer à partir d'un échantillon biologique, et en particulier, mais pas exclusivement, des procédés, des compositions, et des utilisations associées de détection simultanée de la présence de multiples types de cancer (par exemple, le cancer de l'œsophage, le cancer du poumon, le cancer de l'ovaire, le cancer du pancréas, le cancer gastrique, le cancer de la vessie, le cancer du sein, le cancer du col de l'utérus, le cancer colorectal, le cancer de la prostate, le cancer du rein et le cancer de l'utérus) à partir d'un échantillon biologique (par exemple, un échantillon de selles, un échantillon de tissu, un échantillon de sécrétion d'organe, un échantillon de CSF, un échantillon de salive, un échantillon de sang, un échantillon de plasma ou un échantillon d'urine).
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