WO2022120004 APTAMERS AGAINST CLOSTRIDIUM DIFFICILE, COMPOSITIONS COMPRISING APTAMERS AGAINST CLOSTRIDIUM DIFFICILE AND METHODS OF USING THE SAME

Settings

Stemming

Single Family Member

Include NPL

Feedback

Goto Application

Publication Number WO/2022/120004

Publication Date 09.06.2022

International Application No. PCT/US2021/061531

International Filing Date 02.12.2021

IPC

View less classifications

CPC

View more classifications

View less classifications

Applicants

LIV PROCESS, INC. [US]/[US]

Inventors

SHANNON, Ronald J.
PENNER, Gregory

Agents

PHAM, Chinh H.
SALEM, Natalie

Priority Data

17/111,067

03.12.2020

Publication Language English (en)

Filing Language English (EN)

Designated States

View all

Title

(EN) APTAMERS AGAINST CLOSTRIDIUM DIFFICILE, COMPOSITIONS COMPRISING APTAMERS AGAINST CLOSTRIDIUM DIFFICILE AND METHODS OF USING THE SAME

(FR) APTAMÈRES CONTRE CLOSTRIDIUM DIFFICILE, COMPOSITIONS COMPRENANT DES APTAMÈRES CONTRE CLOSTRIDIUM DIFFICILE ET LEURS PROCÉDÉS D'UTILISATION

Abstract

(EN) Compositions comprising optimized aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.

(FR) L'invention concerne des compositions comprenant des aptamères optimisés aptes à se lier spécifiquement à une protéine de surface de spore de Clostridium difficile. L'invention concerne également un procédé de détection, d'enrichissement, de séparation et/ou d'isolement de spores de Clostridium difficile.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
11	DNA or RNA fragments; Modified forms thereof
115	Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q	MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1	Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68	involving nucleic acids

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q	MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1	Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68	involving nucleic acids
6876	Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888	for detection or identification of organisms
689	for bacteria

G	PHYSICS
01	MEASURING; TESTING
N	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33	Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48	Biological material, e.g. blood, urine; Haemocytometers
50	Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53	Immunoassay; Biospecific binding assay; Materials therefor
573	for enzymes or isoenzymes

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
11	DNA or RNA fragments; Modified forms thereof
115	Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith

Processing

National Phase Entries

Authority File

Settings

Feedback

Goto Application

1. WO2022120004 - APTAMERS AGAINST CLOSTRIDIUM DIFFICILE, COMPOSITIONS COMPRISING APTAMERS AGAINST CLOSTRIDIUM DIFFICILE AND METHODS OF USING THE SAME

G	PHYSICS
01	MEASURING; TESTING
N	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21	Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
62	Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63	optically excited
64	Fluorescence; Phosphorescence
6428	Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
6439	with indicators, stains, dyes, tags, labels, marks

G	PHYSICS
01	MEASURING; TESTING
N	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21	Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
62	Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63	optically excited
64	Fluorescence; Phosphorescence
6428	Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"