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1. WO2022119008 - METHOD FOR PRODUCING SCAFFOLD COMPOSITION FOR TISSUE REGENERATION USING NON-SPONTANEOUS EMULSION DISPERSION METHOD

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Publication Number WO/2022/119008
Publication Date 09.06.2022
International Application No. PCT/KR2020/017567
International Filing Date 03.12.2020
IPC
A61L 27/26 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
14Macromolecular materials
26Mixtures of macromolecular materials
A61L 27/56 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
56Porous or cellular materials
A61L 27/52 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
52Hydrogels or hydrocolloids
C08L 67/04 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
67Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
04Polyesters derived from hydroxy carboxylic acids, e.g. lactones
C08L 29/04 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
29Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
02Homopolymers or copolymers of unsaturated alcohols
04Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
CPC
A61L 27/26
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
14Macromolecular materials
26Mixtures of macromolecular compounds
A61L 27/52
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
52Hydrogels or hydrocolloids
A61L 27/56
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
56Porous materials, ; e.g. foams or sponges
C08L 29/04
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
29Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
02Homopolymers or copolymers of unsaturated alcohols
04Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
C08L 67/04
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
67Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain
04Polyesters derived from hydroxycarboxylic acids, e.g. lactones
Applicants
  • (주)리젠바이오참 REGEN BIOCHARM CO., LTD. [KR]/[KR]
Inventors
  • 김경균 KIM, Gyung Gyun
  • 최명 CHOI, Myung
  • 김상진 KIM, Sang Jin
Agents
  • 배영준 BAE, Young Jun
  • 윤의섭 YOON, Eui-Seoup
Priority Data
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PRODUCING SCAFFOLD COMPOSITION FOR TISSUE REGENERATION USING NON-SPONTANEOUS EMULSION DISPERSION METHOD
(FR) MÉTHODE DE PRODUCTION D'UNE COMPOSITION D'ÉCHAFAUDAGE POUR RÉGÉNÉRATION TISSULAIRE À L'AIDE D'UNE MÉTHODE DE DISPERSION D'ÉMULSION NON SPONTANÉE
(KO) 비 자발적 에멀전 확산법을 이용한 조직 재생용 지지체 조성물의 제조방법
front page image
Abstract
(EN) The present invention relates to a method for producing a scaffold composition for tissue regeneration using a non-spontaneous emulsion dispersion method. More specifically, under non-solvent conditions, by using the molecular arrangement characteristic of triblock copolymer [PEOn-PPOm-PEOn] having temperature characteristics and amphiphilicity of biocompatible polymers, a scaffold composition for tissue regeneration is provided in which both crystalline and non-crystalline cultures exhibiting reduced time for hydrolysis and high mechanical strength are present.
(FR) La présente invention concerne une méthode de production d'une composition d'échafaudage pour la régénération tissulaire à l'aide d'une méthode de dispersion d'émulsion non spontanée. Plus spécifiquement, dans des conditions de non-solvant, en utilisant la caractéristique d'agencement moléculaire du copolymère tribloc [PEOn-PPOm-PEOn] ayant des caractéristiques de température et une amphiphilie de polymères biocompatibles, l'invention concerne une composition d'échafaudage pour la régénération tissulaire dans laquelle à la fois des cultures cristallines et des cultures non cristallines présentant un temps réduit d'hydrolyse et une résistance mécanique élevée sont présentes.
(KO) 본 발명은 비 자발적 에멀전 확산법을 이용한 조직 재생용 지지체 조성물의 제조방법에 관한 것으로, 더욱 상세하게는 비 용매하에서 생체적합성 고분자 각각의 온도 특성 및 양친성을 가진 [PEOn-PPOm-PEOn] triblock copolymer의 분자배열특성을 응용하여 가수분해시간을 감소시키면서도 높은 기계적 강도를 나타내는 결정성 배양 및 비 결정성배양이 동시에 존재하는 조직 재생용 지지체 조성물을 제공한다.
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