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1. WO2022115433 - MICRO-ORGANOSPHERES FOR USE IN PERSONALIZED MEDICINE AND DRUG DEVELOPMENT

Publication Number WO/2022/115433
Publication Date 02.06.2022
International Application No. PCT/US2021/060525
International Filing Date 23.11.2021
IPC
G01N 15/00 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
G01N 27/00 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
C12M 1/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
C12M 1/34 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12M 3/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
B01L 3/00 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
CPC
B01L 2200/028
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
02Adapting objects or devices to another
028Modular arrangements
B01L 2200/0652
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0647Handling flowable solids, e.g. microscopic beads, cells, particles
0652Sorting or classification of particles or molecules
B01L 2200/16
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
16Reagents, handling or storing thereof
B01L 2300/0816
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
B01L 2300/0867
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0867Multiple inlets and one sample wells, e.g. mixing, dilution
B01L 2300/0883
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0883Serpentine channels
Applicants
  • XILIS, INC. [US]/[US]
  • DELUBAC, Daniel [FR]/[US]
  • NELSON, Daniel [US]/[US]
  • CALAWAY, John [US]/[US]
  • FREED, Daniel [US]/[US]
Inventors
  • DELUBAC, Daniel
  • NELSON, Daniel
  • CALAWAY, John
  • FREED, Daniel
Agents
  • MAYER, Mika R.
  • WHITTLE, James R.
  • WU, Robert H.
Priority Data
63/118,52725.11.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MICRO-ORGANOSPHERES FOR USE IN PERSONALIZED MEDICINE AND DRUG DEVELOPMENT
(FR) MICRO-ORGANOSPHÈRES UTILISABLES EN MÉDECINE PERSONNALISÉE ET EN DÉVELOPPEMENT DE MÉDICAMENTS
Abstract
(EN) Disclosed herein are systems, apparatuses, and methods for forming micro-organospheres. In some variations, a system may comprise a micro-organosphere generator configured to form a set of micro-organospheres from a mixture of a biological sample and a fluid. A controller may be coupled to an imaging device. The controller may be configured to receive the imaging data corresponding to one or more of the mixture or the set of micro-organospheres, and estimate one or more characteristics of the set of micro-organospheres based at least on the imaging data.
(FR) Des systèmes, des appareils et des procédés de formation de micro-organosphères sont divulgués ici. Selon certaines variantes, un système peut comprendre un générateur de micro-organosphères conçu pour transformer un mélange d'échantillon biologique et de fluide en ensemble de micro-organosphères. Un dispositif de commande peut être couplé à un dispositif d'imagerie. Le dispositif de commande peut être conçu pour recevoir les données d'imagerie correspondant à une ou plusieurs microsphères du mélange ou de l'ensemble de microsphères et pour estimer une ou plusieurs caractéristiques de l'ensemble de microbilles au moins selon les données d'imagerie.
Latest bibliographic data on file with the International Bureau