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1. WO2022076318 - METHODS FOR CONCENTRATING PROTEINS

Publication Number WO/2022/076318
Publication Date 14.04.2022
International Application No. PCT/US2021/053394
International Filing Date 04.10.2021
IPC
C07K 1/34 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
14Extraction; Separation; Purification
34by filtration, ultrafiltration or reverse osmosis
CPC
C07K 1/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
14Extraction; Separation; Purification
34by filtration, ultrafiltration or reverse osmosis
Applicants
  • BRISTOL-MYERS SQUIBB COMPANY [US]/[US]
Inventors
  • HUNG, Jessica Joy
  • HOLSTEIN, Melissa Ann
  • LAM, Shing Fung
  • GHOSE, Sanchayita
Agents
  • KIM, Ji Eun
  • BANOWIT, Donald R.
  • BEMBEN, Richard M.
  • BEZOS, Salvador M.
  • BLOCK, Daniel S.
  • BODENSTEIN, Matthew
  • CALVO, Paul A.
  • CAMARCE, Christian A.
  • CIMBALA, Michele A.
  • COLLER III, Richard D.
  • CONKLIN, Kyle
  • COVERT, John M.
  • DESAI, Nirav N.
  • DURKIN, Tracy-Gene G.
  • EISENBERG, Jason D.
  • ELLISON, Eldora L.
  • ESMOND, Robert W.
  • FEATHERSTONE, Donald J.
  • FITZSIMMONS, Jason A.
  • FRUEAUF, Jeremiah B.
  • GAJEWSKI, Daniel
  • ROSE GILLENTINE, Marsha
  • GLENN, Dallin G.
  • GOLDSTEIN, Jorge A.
  • HELVEY, Jeffrey T.
  • HICKS, Ross
  • HOLOUBEK, Michelle K.
  • HOPFINGER, Todd
  • JACKMAN, Peter A.
  • KENTON, JR., Lestin L.
  • KIM, Josephine
  • LAROCK, Adam C.
  • LEE, Michael Q.
  • LONGSWORTH, Gaby L.
  • MILLONIG, Robert C.
  • MUTSCHELKNAUS, Joseph
  • NANNENGA-COMBS, Bonnie
  • PHERO, Graham C.
  • PICKARD, Byron L.
  • POWERS III, R. Wilson
  • RAY, Michael B.
  • RICHARDSON, Ryan C.
  • RYGIEL, Mark W.
  • SHEA, JR., Timothy J.
  • SOKOHL, Robert E.
  • SPECHT, Michael D.
  • STEFFE, Eric K.
  • STERLING, Deborah A.
  • STERNE, Robert Greene
  • TUMINARO, Jonathan
  • VARUGHESE, Dennies
  • VIRA, Chandrika
  • WRIGHT, Jon E.
  • YONAN, Daniel E.
Priority Data
63/087,71905.10.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR CONCENTRATING PROTEINS
(FR) PROCÉDÉS POUR CONCENTRER DES PROTÉINES
Abstract
(EN) Provided herein are optimized methods for concentrating large volumes of antibody feedstocks to generate concentrated drug substances by ultrafiltration in a batch-like mode using a fed-batch setup.
(FR) La présente invention concerne des procédés optimisés permettant de concentrer de grands volumes de charges d'anticorps pour générer des substances médicamenteuses concentrées par ultrafiltration dans un mode de type discontinu à l'aide d'une installation à alimentation par lots.
Latest bibliographic data on file with the International Bureau