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1. WO2022071581 - SARS-COV-2-BINDING PEPTIDE

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Publication Number WO/2022/071581
Publication Date 07.04.2022
International Application No. PCT/JP2021/036446
International Filing Date 01.10.2021
IPC
C12N 15/13 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
13Immunoglobulins
A61K 39/215 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 16/10 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
CPC
A61K 38/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
02Peptides of undefined number of amino acids; Derivatives thereof
A61K 39/215
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 16/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses ; , e.g. hepatitis E virus
Applicants
  • 株式会社Ｅｐｓｉｌｏｎ　Ｍｏｌｅｃｕｌａｒ　Ｅｎｇｉｎｅｅｒｉｎｇ EPSILON MOLECULAR ENGINEERING, INC. [JP]/[JP]
  • 学校法人北里研究所 THE KITASATO INSTITUTE [JP]/[JP]
  • 花王株式会社 KAO CORPORATION [JP]/[JP]
Inventors
  • 正木　秀和 MASAKI, Hidekazu
  • 熊地　重文 KUMACHI, Shigefumi
  • 米原　涼 YONEHARA, Ryo
  • 松村　佑太 MATSUMURA, Yuta
  • 河野　響 KAWANO, Hibiki
  • 東條　卓人 TOJO, Takuto
  • 森本　拓也 MORIMOTO, Takuya
  • 片山　和彦 KATAYAMA, Kazuhiko
  • 芳賀　慧 HAGA, Kei
  • 戸高　玲子 TODAKA, Reiko
  • 澤田　成史 SAWADA, Akihito
  • 高野　友美 TAKANO, Tomomi
Agents
  • 特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE
Priority Data
2020-16807802.10.2020JP
2020-18526805.11.2020JP
2020-20121203.12.2020JP
2021-08569820.05.2021JP
2021-13437219.08.2021JP
2021-15060415.09.2021JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) SARS-COV-2-BINDING PEPTIDE
(FR) PEPTIDE DE LIAISON AU SARS-COV-2
(JA) ＳＡＲＳ－ＣｏＶ－２結合ペプチド
Abstract
(EN) Provided is a peptide capable of binding to SARS-CoV-2 and a method for utilizing the peptide.　This peptide capable of binding to SARS-CoV-2 has at least one structural domain comprising CDR3 which comprises an amino acid sequence represented by any one of SEQ ID Nos: 1 to 9 or an amino acid sequence having a structure such that at least one amino acid residue in the aforementioned amino acid sequence is substituted by another amino acid residue.
(FR) L'invention concerne un peptide pouvant se lier au SARS-CoV-2 et un procédé d'utilisation du peptide.　Ce peptide pouvant se lier au SARS-CoV-2 a au moins un domaine structural comprenant CDR3 qui comprend une séquence d'acides aminés représentée par l'une quelconque des SEQ ID NO : 1 à 9 ou une séquence d'acides aminés ayant une structure telle qu'au moins un résidu d'acide aminé dans la séquence d'acides aminés susmentionnée est substitué par un autre résidu d'acide aminé.
(JA) ＳＡＲＳ－ＣｏＶ－２に結合するペプチド及びその利用法を提供する。　配列番号１～９のいずれかで示されるアミノ酸配列又は当該アミノ酸配列において少なくとも１つのアミノ酸が他のアミノ酸に置換されたアミノ酸配列からなるＣＤＲ３を含む構造ドメインを１つ以上有する、ＳＡＲＳ－ＣｏＶ－２に結合するペプチド。
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