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1. WO2022070071 - DIHYDROOROTATE DEHYDROGENASE INHIBITORS

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Publication Number WO/2022/070071
Publication Date 07.04.2022
International Application No. PCT/IB2021/058908
International Filing Date 29.09.2021
IPC
A61P 35/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/4375 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
4375the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
CPC
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • JANSSEN BIOTECH, INC. [US]/[US]
Inventors
  • DERATT, Lindsey
  • KUDUK, Scott
Agents
  • SHIRTZ, Joseph F.
  • HORNINGER, Lisa Mead
Priority Data
63/085,31730.09.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DIHYDROOROTATE DEHYDROGENASE INHIBITORS
(FR) INHIBITEURS DE LA DIHYDROOROTATE DÉSHYDROGÉNASE
front page image
Abstract
(EN) Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows, wherein R1, R2, R3, R4, are defined herein.
(FR) L'invention concerne des composés, des compositions et des procédés pour traiter des maladies, des troubles ou des états médicaux qui sont affectés par la modulation de la DHODH. De tels composés sont représentés par la formule (I) comme suit, dans laquelle R1, R2, R3, R4 sont tels que définis dans la description.
Latest bibliographic data on file with the International Bureau
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