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1. WO2022045276 - HETERODIMER FC POLYPEPTIDE

Publication Number WO/2022/045276
Publication Date 03.03.2022
International Application No. PCT/JP2021/031448
International Filing Date 27.08.2021
IPC
C07K 16/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
C12N 15/13 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
13Immunoglobulins
CPC
C07K 16/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
C07K 16/46
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
Applicants
  • 中外製薬株式会社 CHUGAI SEIYAKU KABUSHIKI KAISHA [JP]/[JP]
Inventors
  • 堅田 仁 KATADA, Hitoshi
  • 辰巳 加奈子 TATSUMI, Kanako
Agents
  • 春名 雅夫 HARUNA, Masao
  • 清水 初志 SHIMIZU, Hatsushi
  • 山口 裕孝 YAMAGUCHI, Hirotaka
  • 刑部 俊 OSAKABE, Suguru
  • 井上 隆一 INOUE, Ryuichi
  • 佐藤 利光 SATO, Toshimitsu
  • 新見 浩一 SHIMMI, Hirokazu
  • 小林 智彦 KOBAYASHI, Tomohiko
  • 小寺 秀紀 KODERA, Hideki
  • 大関 雅人 OHZEKI, Masato
  • 川本 和弥 KAWAMOTO, Kazuya
Priority Data
PCT/JP2020/03254728.08.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) HETERODIMER FC POLYPEPTIDE
(FR) POLYPEPTIDE FC HÉTÉRODIMÈRE
(JA) ヘテロ二量体Fcポリペプチド
Abstract
(EN) In non-limiting embodiments, the present invention provides a polypeptide comprising a mutant Fc region which contains an amino acid alteration in a parent Fc region, and a method for producing the polypeptide.
(FR) Dans des modes de réalisation non limitatifs, la présente invention concerne un polypeptide comprenant une région Fc mutante qui contient une modification d'acide aminé dans une région Fc parente, et un procédé de production du polypeptide.
(JA) 非限定的な一実施態様において、親Fc領域においてアミノ酸改変を含む変異Fc領域を含むポリペプチド、および該ポリペプチドの製造方法を提供する。
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