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1. WO2022044033 - QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF

Publication Number WO/2022/044033
Publication Date 03.03.2022
International Application No. PCT/IN2021/050790
International Filing Date 17.08.2021
IPC
C07D 401/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
CPC
C07D 401/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
Applicants
  • COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860)) [IN]/[IN]
Inventors
  • PABBARAJA, Srihari
  • MEHTA, Goverdhan
  • SINGH, Shweta
Agents
  • LAKSHMIKUMARAN, Malathi
  • RAE, Konpal
  • PHILLIPS, Prashant
  • PANDEYA, Jaya
  • SRINIVASAN, T.
Priority Data
20201103628822.08.2020IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF
(FR) COMPOSÉS DE QUINOLONE ET LEUR PROCÉDÉ DE PRÉPARATION
Abstract
(EN) The present invention relates to quinolones of formula (I) and process for its preparation by amine insertion into aryl-ynones thereof. [Formula I] The invention further relates to the process to obtain the natural products such as: graveoline, graveolinine, pseudane IV, pseudane VII, pseudane VIII and pseudane XII. The invention also describes the process for the total synthesis of waltherione F in concise approach from the quinolone synthesized. [Formula II]
(FR) La présente invention concerne des quinolones de formule (I) et un procédé pour leur préparation par insertion d'amine dans des aryl-ynones de celles-ci. [Formule I] L'invention concerne en outre un procédé permettant d'obtenir des produits naturels tels que : la gravéoline, la gravéolinine, le pseudane IV, le pseudane VII, le pseudane VIII et le pseudane XII. L'invention concerne également un procédé destiné à la synthèse totale de waltherione F dans une approche concise à partir de la quinolone synthétisée. [Formule II]
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