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1. WO2022032073 - TRPML MODULATORS

Publication Number WO/2022/032073
Publication Date 10.02.2022
International Application No. PCT/US2021/044911
International Filing Date 06.08.2021
IPC
C12N 15/63 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
CPC
C07D 209/96
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
56Ring systems containing three or more rings
96Spiro-condensed ring systems
Applicants
  • CASMA THERAPEUTICS, INC. [US]/[US]
Inventors
  • MAYNARD, Andrew Thomas
  • MEREDITH, Erik Lee
  • SAUNDERS, Jeffrey Owen
  • LIN, Jian
  • FORTANET, Jorge Garcia
Agents
  • SHINALL, Michael A.
  • ADAMS, Melissa M.
  • ADATO, Ronen
  • BOUZA, Alexandra A.
  • BUTEAU, Kristen C.
  • BYCHOWSKI, Meaghan E.
  • D'AMATO, Erica M.
  • DAUKSS, Dana M.
  • FLYNN, Peter A.
  • HAULBROOK, William R.
  • HERSCHBACH JARRELL, Brenda
  • KAUR, Mandeep
  • KITTO, Rebekah Z.
  • LI, Xiaodong
  • LYON, Charles E.
  • MA, Longle
  • MEDINA, Rolando
  • MONROE, Margo R.
  • PACE, Nicholas J.
  • POLIO, Samuel R.
  • REARICK, John P.
  • REESE, Brian E.
  • SCHMITT, Michael
  • SCHONEWALD, Stephanie L.
  • SHORE, David E.
  • SUBRAMANIAN, Sowmya
  • TSE, Janet M.
  • VETTER, Michael L.
  • VRABLIK, Tracy L.
Priority Data
63/062,94307.08.2020US
63/119,91501.12.2020US
63/186,84611.05.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TRPML MODULATORS
(FR) MODULATEURS DE TRPML
Abstract
(EN) The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
(FR) La présente invention concerne des composés, des compositions pharmaceutiquement acceptables de ceux-ci et des procédés d'utilisation de ceux-ci.
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