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1. WO2022029464 - THE BIOACTIVITY OF CARBONIUOS NANOPARTICLES IN ENRICHMENT OF BLOOD WITH GROWTH FACTORS

Publication Number WO/2022/029464
Publication Date 10.02.2022
International Application No. PCT/IB2020/057301
International Filing Date 01.08.2020
IPC
C07K 14/475 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
A61M 1/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 5/178 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
178Syringes
B01J 20/20 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
02comprising inorganic material
20comprising free carbon; comprising carbon obtained by carbonising processes
C03B 19/10 2006.1
CCHEMISTRY; METALLURGY
03GLASS; MINERAL OR SLAG WOOL
BMANUFACTURE OR SHAPING OF GLASS, OR OF MINERAL OR SLAG WOOL; SUPPLEMENTARY PROCESSES IN THE MANUFACTURE OR SHAPING OF GLASS, OR OF MINERAL OR SLAG WOOL
19Other methods of shaping glass
10Forming beads
CPC
A61M 2205/0238
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2205General characteristics of the apparatus
02characterised by a particular materials
0238the material being a coating or protective layer
C03C 17/28
CCHEMISTRY; METALLURGY
03GLASS; MINERAL OR SLAG WOOL
CCHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
17Surface treatment of glass, not in the form of fibres or filaments, by coating
28with organic material
C03C 23/006
CCHEMISTRY; METALLURGY
03GLASS; MINERAL OR SLAG WOOL
CCHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
23Other surface treatment of glass not in the form of fibres or filaments
0005by irradiation
006by plasma or corona discharge
C07K 14/475
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
Applicants
  • PISHGAHI, Alireza [IR]/[IR]
  • POUR ABBAS KHEIRADDIN, Behzad [IR]/[IR]
  • YOUSEFI, Mehdi [IR]/[IR]
Inventors
  • PISHGAHI, Alireza
  • POUR ABBAS KHEIRADDIN, Behzad
  • YOUSEFI, Mehdi
Priority Data
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) THE BIOACTIVITY OF CARBONIUOS NANOPARTICLES IN ENRICHMENT OF BLOOD WITH GROWTH FACTORS
(FR) BIOACTIVITÉ DE NANOPARTICULES DE CARBONIUOS DANS L'ENRICHISSEMENT DU SANG AVEC DES FACTEURS DE CROISSANCE
Abstract
(EN) This is a description of a novel method for preparation of an autologous serum enriched in growth factors and cytokines. This innovation is a blood-collecting syringe consist of specially coated glass beads with a coating materials. The coating, stimulate peripheral blood mono-nuclear cells to synthetize and release large amount of growth factors and cytokines into the blood sample. The blood sample is processes then by incubation and centrifugation resulting in a cell-free autologous serum. The final autologous serum contains multiple growth factors, anti-inflammatory, pro-inflammatory cytokines and interleukin 1-receptor blocker (IL1-Ra). The final autologous serum prepared by this invention, has preventive, therapeutic and alleviative effects in some human and animal musculoskeletal, dermatologic and pain-related diseases.
(FR) La présente invention concerne un nouveau procédé de préparation d'un sérum autologue enrichi en facteurs de croissance et cytokines. L'invention concerne une seringue de collecte de sang qui est constituée de billes de verre spécialement revêtues avec un matériau de revêtement. Le revêtement, stimule les cellules mono-nucléaires du sang périphérique pour synthétiser et libérer une grande quantité de facteurs de croissance et de cytokines dans l'échantillon de sang. L'échantillon de sang est ensuite traité par incubation et centrifugation conduisant à un sérum autologue exempt de cellules. Le sérum autologue final contient de multiples facteurs de croissance, des cytokines anti-inflammatoires, pro-inflammatoires et un bloqueur du récepteur de l'interleukine 1 (IL1-Ra). Le sérum autologue final préparé selon la présente invention a des effets préventifs, thérapeutiques et atténuateurs dans certaines maladies musculo-squelettiques, dermatologiques et associées à la douleur chez l'homme et l'animal.
Latest bibliographic data on file with the International Bureau