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1. WO2022029164 - EXTRACTING PARAMETERS FOR ANALYTE CONCENTRATION DETERMINATION

Publication Number WO/2022/029164
Publication Date 10.02.2022
International Application No. PCT/EP2021/071743
International Filing Date 04.08.2021
IPC
A61B 5/145 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1495 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1495Calibrating or testing in vivo probes
CPC
A61B 2560/0223
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
02Operational features
0223of calibration, e.g. protocols for calibrating sensors
A61B 5/0002
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
A61B 5/1451
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14507specially adapted for measuring characteristics of body fluids other than blood
1451for interstitial fluid
A61B 5/14532
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14532for measuring glucose, e.g. by tissue impedance measurement
A61B 5/1486
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
1486using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/14865
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
1486using enzyme electrodes, e.g. with immobilised oxidase
14865invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
Applicants
  • ASCENSIA DIABETES CARE HOLDINGS AG [CH]/[CH]
Inventors
  • WU, Huan-Ping
  • CERUTTI, Mark D.
  • HARRISON, Bern
Agents
  • COHAUSZ & FLORACK PATENT- UND RECHTSANWÄLTE PARTNERSCHAFTSGESELLSCHAFT MBB, HENDRIK BÜCKER
Priority Data
63/061,13504.08.2020US
63/061,15204.08.2020US
63/061,15704.08.2020US
63/061,16704.08.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) EXTRACTING PARAMETERS FOR ANALYTE CONCENTRATION DETERMINATION
(FR) EXTRACTION DE PARAMÈTRES À DES FINS DE DÉTERMINATION DE CONCENTRATION D'ANALYTE
Abstract
(EN) A method of determining glucose values during continuous glucose monitoring (CGM) measurements includes providing a CGM device including a sensor, a memory, and a processor; applying a constant voltage potential to the sensor; measuring a primary current signal resulting from the constant voltage potential and storing the measured primary current signal in the memory; applying a probing potential modulation sequence to the sensor; measuring probing potential modulation current signals resulting from the probing potential modulation sequence and storing measured probing potential modulation current signals in the memory; determining an initial glucose concentration based on a conversion function and a ratio of measured probing potential modulation current signals; determining a connection function value based on the primary current signal and a plurality of the probing potential modulation current signals; and determining a final glucose concentration based on the initial glucose concentration and the connection function value. Other aspects are disclosed.
(FR) L'invention concerne un procédé de détermination de valeurs de glucose lors de mesures de surveillance continue de glucose (CGM) consistant à utiliser un dispositif de CGM comprenant un capteur, une mémoire et un processeur ; à appliquer un potentiel de tension constant au capteur ; à mesurer un signal de courant primaire consécutif au potentiel de tension constant et à mémoriser le signal de courant primaire mesuré dans la mémoire ; à appliquer une séquence de modulation de potentiel de sondage au capteur ; à mesurer des signaux de courant de modulation de potentiel de sondage consécutifs à la séquence de modulation de potentiel de sondage et à mémoriser les signaux de courant de modulation de potentiel de sondage mesurés dans la mémoire ; à déterminer une concentration de glucose initiale sur la base d'une fonction de conversion et d'un taux de signaux de courant de modulation de potentiel de sondage mesurés ; à déterminer une valeur de fonction de connexion sur la base du signal de courant primaire et d'une pluralité des signaux de courant de modulation de potentiel de sondage ; et à déterminer une concentration de glucose finale sur la base de la concentration de glucose initiale et de la valeur de fonction de connexion. L'invention divulgue d'autres aspects.
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