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1. WO2022026902 - CHIMERIC PROTEINS AND METHODS OF USE FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Publication Number WO/2022/026902
Publication Date 03.02.2022
International Application No. PCT/US2021/044019
International Filing Date 30.07.2021
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 15/62 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
62DNA sequences coding for fusion proteins
CPC
A61K 38/30
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
30Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • SILVER CREEK PHARMACEUTICALS, INC. [US]/[US]
Inventors
  • PFAFF, Samuel J.
  • ZHANG, Yan
  • KUCHENBECKER, Kristopher M.
  • CHAWLA, Lakhmir S.
Agents
  • DYKEMAN, David J.
  • SALEM, Natalie
Priority Data
17/390,20630.07.2021US
63/058,88830.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) CHIMERIC PROTEINS AND METHODS OF USE FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
(FR) PROTÉINES CHIMÉRIQUES ET MÉTHODES D'UTILISATION POUR LE TRAITEMENT DE TROUBLES DU SYSTÈME NERVEUX CENTRAL
Abstract
(EN) Aspects of the present disclosure relate generally to kits and methods for treating acute central nervous systems disorders with chimeric proteins and pharmaceutical compositions comprising such chimeric proteins.
(FR) Des aspects de la présente divulgation concernent d'une manière générale des kits et des méthodes de traitement de troubles aigus du système nerveux central au moyen de protéines chimériques et de compositions pharmaceutiques comprenant de telles protéines chimériques.
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