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1. WO2022026255 - TECHNIQUES FOR NON-INVASIVE DETERMINATION OF ESTIMATED CARDIAC OUTPUT DURING DIALYSIS TREATMENT

Publication Number WO/2022/026255
Publication Date 03.02.2022
International Application No. PCT/US2021/042463
International Filing Date 21.07.2021
IPC
A61M 1/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
A61M 1/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
16with membranes
A61B 5/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
A61B 5/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 5/029 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026Measuring blood flow
029Measuring blood output from the heart, e.g. minute volume
A61B 5/145 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
CPC
A61B 5/0075
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0075by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
A61B 5/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
A61B 5/02028
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
02028Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
A61B 5/029
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
026Measuring blood flow
029Measuring or recording blood output from the heart, e.g. minute volume
A61B 5/0816
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
0816Measuring devices for examining respiratory frequency
A61B 5/14535
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14535for measuring haematocrit
Applicants
  • FRESENIUS MEDICAL CARE HOLDINGS, INC. [US]/[US]
Inventors
  • KOTANKO, Peter
  • THIJSSEN, Stephan
  • CAMPOS, Israel
  • ZHANG, Hanje
Agents
  • BANNISTER, Trevor L.
  • LOCKWOOD, Kurt
Priority Data
16/939,31227.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TECHNIQUES FOR NON-INVASIVE DETERMINATION OF ESTIMATED CARDIAC OUTPUT DURING DIALYSIS TREATMENT
(FR) TECHNIQUES DE DÉTERMINATION NON INVASIVE DU DÉBIT CARDIAQUE ESTIMÉ AU COURS D'UN TRAITEMENT DE DIALYSE
Abstract
(EN) Techniques and apparatuses for determining an estimated cardiac output for a patient during dialysis treatment are described. In one embodiment, for example, an apparatus may include a memory and logic coupled to the memory. The logic may be configured to determine an upper body oxygen consumption for a patient, determine, during a dialysis process: a hemoglobin concentration and a venous oxygen saturation measured via an optical blood monitor operably coupled to an extracorporeal circuit of a dialysis system performing the dialysis process,; an arterial oxygen saturation measured via a pulse oximeter operably coupled to the extracorporeal circuit; an arterial-venous oxygen content difference based on the arterial oxygen saturation and the venous oxygen saturation; and an upper body blood flow (UBBF) as (upper body oxygen consumption)/(arterial-venous oxygen content difference), and determine a treatment recommendation based on the upper body blood flow. Other embodiments are described.
(FR) Sont décrits, des techniques et des appareils pour déterminer un débit cardiaque estimé pour un patient au cours d'un traitement de dialyse. Dans un mode de réalisation, par exemple, un appareil peut comprendre au moins une mémoire et une logique couplée à la mémoire. La logique peut être configurée pour déterminer une consommation d'oxygène corporelle supérieure pour un patient, pour déterminer, au cours d'un processus de dialyse : une concentration d'hémoglobine et une saturation veineuse en oxygène mesurées par l'intermédiaire d'un dispositif optique de surveillance du sang couplé de manière fonctionnelle à un circuit extracorporel d'un système de dialyse effectuant le processus de dialyse ; une saturation artérielle en oxygène mesurée par l'intermédiaire d'un oxymètre de pouls couplé de manière fonctionnelle au circuit extracorporel ; une différence de teneur en oxygène artério-veineuse basée sur la saturation artérielle en oxygène et la saturation veineuse en oxygène ; et une circulation sanguine du haut du corps (UBBF) en tant que (consommation en oxygène du haut du corps)/(différence de teneur en oxygène artério-veineuse), et pour déterminer une recommandation de traitement sur la base de la circulation sanguine du haut du corps. D'autres modes de réalisation sont décrits.
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