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1. WO2022024385 - COMPOSITION CONTAINING COMPONENT DERIVED FROM CONNARUS OR ZANTHOXYLUM FRUIT

Publication Number WO/2022/024385
Publication Date 03.02.2022
International Application No. PCT/JP2020/029558
International Filing Date 31.07.2020
IPC
A61P 19/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 21/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
06Anabolic agents
A61K 36/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
A61K 36/758 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
75Rutaceae (Rue family)
758Zanthoxylum, e.g. pricklyash
A23L 33/105 2016.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
CPC
A23L 33/105
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 36/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
A61K 36/758
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
75Rutaceae (Rue family)
758Zanthoxylum, e.g. pricklyash
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 21/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
06Anabolic agents
Applicants
  • 株式会社ファルマクリエ神戸 PHARMA CREA KOBE CO. LTD. [JP]/[JP]
Inventors
  • 谷口 泰造 TANIGUCHI, Taizo
  • 松本 衣代 MATSUMOTO, Kinuyo
  • 新田 祐子 NITTA, Yuko
  • 片桐 稔 KATAGIRI, Minoru
Agents
  • 山本 秀策 YAMAMOTO, Shusaku
  • 森下 夏樹 MORISHITA, Natsuki
  • 飯田 貴敏 IIDA, Takatoshi
  • 石川 大輔 ISHIKAWA, Daisuke
  • 山本 健策 YAMAMOTO, Kensaku
Priority Data
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) COMPOSITION CONTAINING COMPONENT DERIVED FROM CONNARUS OR ZANTHOXYLUM FRUIT
(FR) COMPOSITION CONTENANT UN CONSTITUANT DÉRIVÉ DE CONNARUS OU DE FRUITS DE ZANTHOXYLUM
(JA) 山椒またはコンナルスに由来する成分を含有する組成物
Abstract
(EN) The populations of industrialized countries around the world are rapidly aging. In order for aged individuals to stay healthy both physically and mentally, the maintenance of muscle mass and bone mass is instrumental; however, aged individuals often undergo a reduction in muscle mass and bone mass caused not only by advancing age but also as symptoms of disuse syndrome resulting from reduced physical activity or prolonged inactivity. Consequently, there has been a need for a composition that can be used to augment muscle mass and bone mass, particularly in aged individuals. The inventors of the present invention discovered that disuse syndrome can be effectively prevented or treated with Zanthoxylum fruit, a spice that has been used since early times as food and herbal medicine in the Orient, and Connarus, plants in the family of Connaraceae native to Brazil, and thus have achieved the present invention.
(FR) Les populations de pays industrialisés autour du monde vieillissent rapidement. Afin que les individus âgés restent en bonne santé, à la fois physiquement et mentalement, la conservation de la masse musculaire et de la masse osseuse est déterminante; cependant, les individus âgés subissent souvent une réduction de la masse musculaire et de la masse osseuse provoquée non seulement par l'avancement de l'âge mais également en tant que symptômes du syndrome d'inactivité résultant d'une activité physique réduite ou d'une inactivité prolongée. Par conséquent, il existe un besoin pour une composition qui peut être utilisée pour augmenter la masse musculaire et la masse osseuse, en particulier chez des individus âgés. Les inventeurs de la présente invention ont découvert que le syndrome d'inactivité peut être efficacement prévenu ou traité avec le fruit de Zanthoxylum, une épice qui a été utilisée depuis des temps précoces comme aliment et médicament à base d'herbes en Orient et avec le Connarus, des plantes dans la famille de Connaraceae originaires du Brésil et ainsi ont obtenu la présente invention.
(JA) 世界中の先進国では人口の高齢化が進んでいる。高齢者が心身ともに健康で過ごすためには、筋肉量および骨量の維持が重要であるが、高齢者においては、加齢による筋肉量および骨量の減少のみならず、身体活動の低下または長期的な不活動に起因する廃用症候群の症状としての筋肉量および骨量の減少が引き起こされる。そのため、特に高齢者において、筋肉量および骨量を増強させるための組成物が必要であった。発明者らは、東洋において古くから食品および漢方薬として使われてきたスパイスである山椒、およびブラジル原産のマメモドキ科の植物であるコンナルスが廃用症候群の予防または処置に有用であることを見出し、この発明を完成した。
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