Processing

Please wait...

Settings

Settings

Goto Application

1. WO2022023540 - SERUM ALBUMIN-BINDING POLYPEPTIDES

Publication Number WO/2022/023540
Publication Date 03.02.2022
International Application No. PCT/EP2021/071421
International Filing Date 30.07.2021
IPC
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 14/81 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
81Protease inhibitors
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
C07K 14/765
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
76Albumins
765Serum albumin, e.g. HSA
C07K 14/8139
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
81Protease inhibitors
8107Endopeptidase (E.C. 3.4.21-99) inhibitors
8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
C07K 16/2818
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2818against CD28 or CD152
C07K 2319/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
Applicants
  • AVACTA LIFE SCIENCES LIMITED [GB]/[GB]
Inventors
  • JENKINS, Emma
  • ADAM, Estelle
  • STANLEY, Emma
  • BASRAN, Amrik
  • VINCENT, Matthew P.
Agents
  • HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB
Priority Data
63/059,02630.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SERUM ALBUMIN-BINDING POLYPEPTIDES
(FR) POLYPEPTIDES DE LIAISON DE SÉRUMALBUMINE
Abstract
(EN) Provided herein, in some embodiments, are recombinantly engineered variant of stefin polypeptides (AFFIMER® polypeptides) that binds to human serum albumin and extends the half-life of the polypeptides. Also provided herein, in some embodiments, are composition containing the polypeptides, methods of using the polypeptides, and methods of producing the polypeptides.
(FR) Dans certains modes de réalisation, la présente invention concerne, dans certains modes de réalisation, des variants génétiquement modifiés de polypeptides de stefin (polypeptides AFFIMER®) qui se lient à la sérumalbumine humaine et qui prolongent la demi-vie des polypeptides. L'invention concerne également, dans certains modes de réalisation, des compositions contenant les polypeptides, des méthodes d'utilisation des polypeptides et des procédés de production des polypeptides.
Latest bibliographic data on file with the International Bureau