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1. WO2022023233 - BIOMARKERS FOR DIAGNOSING AND MONITORING LUNG CANCER

Publication Number WO/2022/023233
Publication Date 03.02.2022
International Application No. PCT/EP2021/070781
International Filing Date 26.07.2021
IPC
C12Q 1/6886 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/112
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
112Disease subtyping, staging or classification
C12Q 2600/118
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
118Prognosis of disease development
C12Q 2600/154
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
154Methylation markers
Applicants
  • LES LABORATOIRES SERVIER [FR]/[FR]
  • UNIVERSITÉ PARIS CITÉ [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR]/[FR]
  • INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) [FR]/[FR]
  • ASSISTANCE PUBLIQUE HOPITAUX DE PARIS [FR]/[FR]
  • SORBONNE UNIVERSITE [FR]/[FR]
Inventors
  • LOCKHART, Brian
  • GUIGAL-STEPHAN, Nolwen
  • XUEREB, Laura
  • TALY, Valérie
  • LAURENT-PUIG, Pierre
  • WANG-RENAULT, Shufang
  • BLONS, Hélène
Common Representative
  • LES LABORATOIRES SERVIER
Priority Data
20315363.027.07.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) BIOMARKERS FOR DIAGNOSING AND MONITORING LUNG CANCER
(FR) BIOMARQUEURS POUR DIAGNOSTIQUER ET SURVEILLER LE CANCER DU POUMON
Abstract
(EN) The present invention relates to the field of oncology, particularly the early diagnostic of lung cancer, the monitoring of lung cancer patients and the prediction of the clinical outcome of patients. The invention relates to a method for diagnosing lung cancer or diagnosing relapse of lung cancer in patients by determination of the level of methylation of gene(s) and the kit to implement said method.
(FR) La présente invention concerne le domaine de l'oncologie, en particulier le diagnostic précoce du cancer du poumon, la surveillance de patients atteints d'un cancer du poumon et la prédiction du résultat clinique de patients. L'invention concerne un procédé de diagnostic du cancer du poumon ou de diagnostic d'une rechute du cancer du poumon chez des patients par détermination du niveau de méthylation d'au moins un gène, ainsi que le nécessaire pour la mise en oeuvre dudit procédé.
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