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1. WO2022021734 - ULTRASONIC SOUND FIELD CONFORMAL GENE TRANSFECTION DEVICE

Publication Number WO/2022/021734
Publication Date 03.02.2022
International Application No. PCT/CN2020/135338
International Filing Date 10.12.2020
IPC
C12M 1/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
C12M 1/42 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
42Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
C12N 15/87 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
CPC
C12M 35/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
35Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
Applicants
  • 中国科学院深圳先进技术研究院 SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES [CN]/[CN]
Inventors
  • 严飞 YAN, Fei
  • 蒋天安 JIANG, Tianan
  • 谢丽婷 XIE, Liting
  • 邹俊杰 ZOU, Junjie
Agents
  • 深圳中一联合知识产权代理有限公司 SHENZHEN ZHONGYI UNION INTELLECTUAL PROPERTY AGENCY CO., LTD.
Priority Data
202010734848.227.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) ULTRASONIC SOUND FIELD CONFORMAL GENE TRANSFECTION DEVICE
(FR) DISPOSITIF DE TRANSFECTION DE GÈNE CONFORME À UN CHAMP SONORE ULTRASONORE
(ZH) 一种超声声场适形的基因转染装置
Abstract
(EN) An ultrasonic sound field conformal gene transfection device, comprising: an ultrasonic transducer (1), used for emitting an ultrasonic wave; an ultrasonic sound field conformal device (2), used for accommodating a compound of a gene, a cell, and an ultrasound-responsive particle, the shape and size of the ultrasonic sound field conformal device (2) being determined according to a sound field of the ultrasonic wave; and a focal length adapter (3), used for fixing the ultrasonic sound field conformal device (2) at a preset position, the preset position being determined according to the sound field position of the ultrasonic wave.
(FR) Dispositif de transfection génétique conforme au champ sonore ultrasonique, comprenant les éléments suivants : un transducteur ultrasonique (1), utilisé pour émettre une onde ultrasonique; un dispositif conforme au champ sonore ultrasonique (2), utilisé pour recevoir un composé d'un gène, une cellule, et une particule sensible aux ultrasons, la forme et la taille du dispositif conforme au champ sonore ultrasonique (2) étant déterminées selon un champ sonore de l'onde ultrasonique; et un adaptateur de longueur focale (3), utilisé pour fixer le dispositif de conformation de champ sonore ultrasonique (2) à une position prédéfinie, la position prédéfinie étant déterminée en fonction de la position du champ sonore de l'onde ultrasonique.
(ZH) 一种超声声场适形的基因转染装置,包括:超声换能器(1),用于发射超声波;超声声场适形器(2),用于容纳基因、细胞和超声响应颗粒的复合物,所述超声声场适形器(2)的形状以及大小根据所述超声波的声场进行确定;焦距适配器(3),用于将所述超声声场适形器(2)固定于预设位置,所述预设位置根据所述超声波的声场位置进行确定。
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