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1. WO2022011311 - METHODS OF PROTECTING CELLS FROM INSULTS

Publication Number WO/2022/011311
Publication Date 13.01.2022
International Application No. PCT/US2021/041172
International Filing Date 09.07.2021
IPC
A61K 35/12 2015.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
C12Q 1/02 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
02involving viable microorganisms
C12Q 1/68 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
A61K 31/77
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
765Polymers containing oxygen
77of oxiranes
A61P 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
Applicants
  • MUSC FOUNDATION FOR RESEARCH DEVELOPMENT [US]/[US]
Inventors
  • YOST, Michael
  • DENNIS, Sarah Grace
  • WARREN, Graham
Agents
  • MILLER, Carin
  • NIX, F. Brent
Priority Data
63/050,07509.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF PROTECTING CELLS FROM INSULTS
(FR) MÉTHODES DE PROTECTION DE CELLULES CONTRE DES AGRESSIONS
Abstract
(EN) Described herein are methods for preventing non-insulted cell damage during a subject's exposure to radiation. In some embodiments, the method can include administering an amount of poloxamer 188 or a pharmaceutical formulation thereof to a subject prior to exposure to an insult.
(FR) Sont décrites ici des méthodes pour prévenir une lésion de cellules non agressées pendant l'exposition d'un sujet à un rayonnement. Dans certains modes de réalisation, la méthode peut comprendre l'administration d'une quantité de poloxamère 188 ou d'une formulation pharmaceutique de celui-ci à un sujet avant l'exposition à une agression.
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