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1. WO2022011247 - TARGETED DRUG DELIVERY TO SITES OF INTRAVASCULAR OCCLUSION

Publication Number WO/2022/011247
Publication Date 13.01.2022
International Application No. PCT/US2021/041067
International Filing Date 09.07.2021
IPC
A61K 9/50 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
G01N 33/555 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
554the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
555Red blood cell
C12N 9/14 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
C07K 16/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
Applicants
  • CHILDREN'S MEDICAL CENTER CORPORATION [US]/[US]
Inventors
  • PARK, Shin-young
  • SILBERSTEIN, Leslie, E.
  • RYU, Jina
  • LIU, Min
Agents
  • EL-HAYEK, Roque
  • BAKER, C., Hunter
  • AMUNDSEN, Eric, L.
  • ALAM, Saad
  • ATTISHA, Michael, J.
Priority Data
63/050,47710.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TARGETED DRUG DELIVERY TO SITES OF INTRAVASCULAR OCCLUSION
(FR) ADMINISTRATION DE MÉDICAMENT CIBLÉ À DES SITES D'OCCLUSION INTRAVASCULAIRE
Abstract
(EN) Provided herein, in some aspects, are compositions comprising vasoocclusion- inhibiting agents encapsulated in RBCs and uses thereof for treating blood vessel occlusion (e.g., in Sickle Cell Disease).
(FR) L'invention, selon certains aspects, concerne des compositions comprenant des agents inhibiteurs de vaso-occlusion encapsulés dans des érythrocytes et leurs utilisations dans le traitement d'une occlusion de vaisseau sanguin (lors, (par exemple, d'une anémie falciforme).
Latest bibliographic data on file with the International Bureau