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1. WO2022011197 - COMPOSITIONS AND METHODS FOR DETECTION OF LUNG CANCER

Publication Number WO/2022/011197
Publication Date 13.01.2022
International Application No. PCT/US2021/040971
International Filing Date 08.07.2021
IPC
C12Q 1/68 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C12Q 1/6804 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6804Nucleic acid analysis using immunogens
C12Q 1/6818 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
6818involving interaction of two or more labels, e.g. resonant energy transfer
G01N 33/574 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
Applicants
  • MERCY BIOANALYTICS, INC. [US]/[US]
Inventors
  • SEDLAK, Joseph Charles
  • BORTOLIN, Laura Teresa
  • SALEM, Daniel Parker
  • WINN-DEEN, Emily Susan
  • GUSENLEITNER, Daniel
  • COUVILLON, Anthony David
Agents
  • TSE, Janet M.
  • ADAMS, Melissa M.
  • ADATO, Ronen
  • BOUZA, Alexandra A.
  • BUTEAU, Kristen C.
  • BYCHOWSKI, Meaghan E.
  • D'AMATO, Erica M.
  • DAUKSS, Dana M.
  • FLYNN, Peter A.
  • HAULBROOK, William R.
  • HERSCHBACH JARRELL, Brenda
  • KAUR, Mandeep
  • KITTO, Rebekah Z.
  • LI, Xiaodong
  • LYON, Charles E.
  • MA, Longle
  • MEDINA, Rolando
  • MONROE, Margo R.
  • PACE, Nicholas J.
  • POLIO, Samuel R.
  • REARICK, John P.
  • REESE, Brian E.
  • SCHMITT, Michael
  • SCHONEWALD, Stephanie L.
  • SHINALL, Michael A.
  • SHORE, David E.
  • SUBRAMANIAN, Sowmya
  • VETTER, Michael L.
  • VRABLIK, Tracy L.
Priority Data
63/049,53808.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR DETECTION OF LUNG CANCER
(FR) COMPOSITIONS ET MÉTHODES POUR LA DÉTECTION DU CANCER DU POUMON
Abstract
(EN) The present disclosure in one aspect provides technologies for detection of lung cancer, e.g, early detection of lung cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to lung cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g, by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.
(FR) La présente divulgation, selon un aspect, fournit des technologies pour la détection du cancer du poumon, p. ex., la détection précoce du cancer du poumon. Selon un autre aspect, les technologies fournies par la présente sont utiles pour sélectionner et/ou surveiller et/ou évaluer l'efficacité d'un traitement administré à un sujet déterminé comme ayant ou étant susceptible d'avoir un cancer du poumon. Dans certains modes de réalisation, les technologies fournies ici sont utiles pour le développement de diagnostics compagnons, par exemple, en mesurant les charges tumorales et les changements de charges tumorales conjointement avec des agents thérapeutiques.
Latest bibliographic data on file with the International Bureau