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1. WO2022011120 - MODULATORS OF THR-β AND METHODS OF USE THEREOF

Publication Number WO/2022/011120
Publication Date 13.01.2022
International Application No. PCT/US2021/040855
International Filing Date 08.07.2021
IPC
A61P 1/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
18for pancreatic disorders, e.g. pancreatic enzymes
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/4353 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
Applicants
  • ALIGOS THERAPEUTICS, INC. [US]/[US]
Inventors
  • MCGOWAN, David Craig
  • RABOISSON, Pierre Jean-Marie Bernard
  • VANDYCK, Koen
  • DEVAL, Jerome
Agents
  • SCHORR, Kristel
  • LEE-DUTRA, Alice
  • MOCK, Jason N.
Priority Data
63/050,44710.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MODULATORS OF THR-β AND METHODS OF USE THEREOF
(FR) MODULATEURS DE THR-β ET MÉTHODES D'UTILISATION DE CEUX-CI
Abstract
(EN) Disclosed herein are compounds of Formula I': or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a patient with one or more of the above compounds.
(FR) L'invention concerne des composés de formule I' : ou un stéréoisomère ou un tautomère de ceux-ci, ou un sel pharmaceutiquement acceptable de ceux-ci, des compositions pharmaceutiques comprenant de tels composés, et des méthodes de traitement d'une maladie par administration d'un ou plusieurs des composés ci-dessus à un patient ou par mise en contact de ce patient avec lesdits composés.
Latest bibliographic data on file with the International Bureau