Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Tuesday 25.01.2022 at 12:00 PM CET
Settings

Settings

Goto Application

1. WO2022011092 - NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN IMMUNE RESPONSE AGAINST SARS-COV-2

Publication Number WO/2022/011092
Publication Date 13.01.2022
International Application No. PCT/US2021/040811
International Filing Date 08.07.2021
IPC
A61K 9/127 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61K 9/51 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
51Nanocapsules
A61K 31/7105 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A61K 31/7115 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
Applicants
  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US]/[US]
Inventors
  • PARDI, Norbert
  • WEISSMAN, Drew
Agents
  • FONVILLE, Natalie
  • ARTIS, Ryan
  • ALLEN, Justin
  • ALLEN, Scott
  • CHEN, Ming
Priority Data
63/049,29508.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN IMMUNE RESPONSE AGAINST SARS-COV-2
(FR) ARN MODIFIÉ PAR NUCLÉOSIDE POUR INDUIRE UNE RÉPONSE IMMUNITAIRE CONTRE LE VIRUS SARS-COV-2
Abstract
(EN) The present invention relates to compositions and methods for inducing an adaptive immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a SARS-CoV-2 antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a SARS-CoV-2 antigen, adjuvant, or a combination thereof.
(FR) La présente invention concerne des compositions et des méthodes permettant d'induire, chez un sujet, une réponse immunitaire adaptative contre le coronavirus du syndrome respiratoire aigu sévère (SARS-COV-2) chez un sujet. Dans certains modes de réalisation, la présente invention concerne une composition comprenant une molécule d'acide nucléique modifié par nucléoside, codant pour un antigène du SARS-COV-2, un adjuvant, ou une combinaison de ceux-ci. Par exemple, dans certains modes de réalisation, la composition comprend un vaccin comprenant une molécule d'acide nucléique modifié par nucléoside, codant pour un antigène du SARS-COV-2, un adjuvant, ou une combinaison de ceux-ci.
Latest bibliographic data on file with the International Bureau