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1. WO2022010928 - METHOD FOR ENHANCING HUMORAL IMMUNITY

Publication Number WO/2022/010928
Publication Date 13.01.2022
International Application No. PCT/US2021/040558
International Filing Date 06.07.2021
IPC
A61K 38/20 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
19Cytokines; Lymphokines; Interferons
20Interleukins
A61K 39/39 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 31/20 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
A61K 39/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
CPC
A61K 2039/545
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
545characterised by the dose, timing or administration schedule
A61K 2039/555
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
A61K 2039/55505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55505Inorganic adjuvants
A61K 2039/55533
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55522Cytokines; Lymphokines; Interferons
55527Interleukins
55533IL-2
A61K 2039/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
57characterised by the type of response, e.g. Th1, Th2
575humoral response
A61K 2039/6037
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
60characteristics by the carrier linked to the antigen
6031Proteins
6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Applicants
  • NEKTAR THERAPEUTICS (INDIA) PVT. LTD. [IN]/[IN]
  • NEKTAR THERAPEUTICS [US]/[US]
Inventors
  • MIYAZAKI, Takahiro
  • ADDEPALLI, Murali Krishna
Agents
  • EVANS, Susan T.
  • MAHONEY, Jacqueline F.
  • WILSON, Mark A.
Priority Data
20204102874506.07.2020IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR ENHANCING HUMORAL IMMUNITY
(FR) MÉTHODE D'AMÉLIORATION DE L'IMMUNITÉ HUMORALE
Abstract
(EN) The present disclosure provides, among other things, methods, compositions, and kits for promoting or enhancing humoral immunity in a subject. More particularly, provided is a method for enhancing humoral immunity in a subject by administering to the subject a long acting IL-2Rαβ-biased agonist in combination with a vaccine, such as, for example, a preventative vaccine for protection against an infectious disease.
(FR) La présente divulgation concerne, entre autres, des méthodes, des compositions et des kits pour favoriser ou améliorer l'immunité humorale chez un sujet. Plus particulièrement, l'invention concerne une méthode d'amélioration de l'immunité humorale chez un sujet par administration au sujet d'un agoniste dirigé de l'IL-2 Rαβ à action prolongée en association avec un vaccin, comme par exemple un vaccin préventif de protection contre une maladie infectieuse.
Latest bibliographic data on file with the International Bureau