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1. WO2022010764 - MUCOPENETRATING FORMULATIONS

Publication Number WO/2022/010764
Publication Date 13.01.2022
International Application No. PCT/US2021/040244
International Filing Date 02.07.2021
IPC
A61K 48/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C12N 15/11 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
C12N 15/88 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
88using microencapsulation, e.g. using liposome vesicle
Applicants
  • VIVTEX CORPORATION [US]/[US]
Inventors
  • VON ERLACH, Thomas
Agents
  • DIPIETRANTONIO, Heather, J.
  • ALAM, Saad
  • BAKER, C., Hunter
  • ATTISHA, Michael, J.
  • AMUNDSEN, Eric, L.
Priority Data
63/048,61706.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MUCOPENETRATING FORMULATIONS
(FR) FORMULATIONS MUCO-PÉNÉTRANTES
Abstract
(EN) Disclosed herein are compositions and kits comprising a mucopenetrating substance, a therapeutic nucleic acid, and a cationic polymer in an amount sufficient to charge neutralize the therapeutic nucleic acid. Also provided herein are methods of using and producing the compositions and kits.
(FR) L'invention divulgue des compositions et des kits comprenant une substance muco-pénétrante, un acide nucléique thérapeutique et un polymère cationique en une quantité suffisante pour neutraliser la charge de l'acide nucléique thérapeutique. L'invention concerne également des méthodes d'utilisation et de production des compositions et des kits.
Latest bibliographic data on file with the International Bureau