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1. WO2022010760 - DUAL-PUMP SYSTEM FOR DELIVERING EMBOLIC BEADS OR OTHER THERAPEUTIC SUBSTANCES INTO AN ARTERY

Publication Number WO/2022/010760
Publication Date 13.01.2022
International Application No. PCT/US2021/040235
International Filing Date 02.07.2021
IPC
A61M 5/142 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
142Pressure infusion, e.g. using pumps
A61M 5/168 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
A61M 25/10 2013.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
25Catheters; Hollow probes
10Balloon catheters
A61M 5/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
Applicants
  • ENDOBAR SOLUTIONS LLC [US]/[US]
Inventors
  • KIPSHIDZE, Nicholas
  • RAHIMZADEH, Jason
  • LEVIT, Eran
Agents
  • MAYER, Robert S.
Priority Data
16/922,72207.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DUAL-PUMP SYSTEM FOR DELIVERING EMBOLIC BEADS OR OTHER THERAPEUTIC SUBSTANCES INTO AN ARTERY
(FR) SYSTÈME À DOUBLE POMPE PERMETTANT D'ADMINISTRER DES BILLES EMBOLIQUES OU D'AUTRES SUBSTANCES THÉRAPEUTIQUES DANS UNE ARTÈRE
Abstract
(EN) A suspension of a therapeutic substance (e.g., embolic beads) dispersed within a liquid can be delivered via a catheter by using a bidirectional pump to rapidly draw the mixture of the therapeutic substance and liquid from an external syringe into an internal reservoir, then rapidly push the mixture back out into the external syringe. The rapid operation of the bidirectional pump mixes the two constituents so that the therapeutic substance is temporarily suspended within the liquid. Then, a low-speed pump is used to inject the mixture out via the catheter. In some embodiments, the parameters of the low-speed pump are controlled so that the fluid exiting the catheter will experience laminar flow. When the therapeutic substance comprises embolic beads, this can advantageously prevent reflux of the embolic beads, which can be dangerous.
(FR) Suspension d'une substance thérapeutique (p. ex., des billes emboliques) dispersée dans un liquide, pouvant être distribuée par l'intermédiaire d'un cathéter à l'aide d'une pompe bidirectionnelle permettant d'aspirer rapidement le mélange de la substance thérapeutique et du liquide d'une seringue externe dans un réservoir interne, puis de repousser rapidement le mélange dans la seringue externe. Le fonctionnement rapide de la pompe bidirectionnelle mélange les deux constituants de telle sorte que la substance thérapeutique est suspendue temporairement dans le liquide. Ensuite, une pompe à basse vitesse est utilisée pour injecter le mélange vers l'extérieur par l'intermédiaire du cathéter. Dans certains modes de réalisation, les paramètres de la pompe à basse vitesse sont commandés de telle sorte que le fluide sortant du cathéter subit un écoulement laminaire. Lorsque la substance thérapeutique comprend des billes emboliques, cela peut empêcher avantageusement le reflux des billes emboliques, ce qui peut être dangereux.
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