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1. WO2022010683 - TOPICAL VITAMIN C COMPOSITION

Publication Number WO/2022/010683
Publication Date 13.01.2022
International Application No. PCT/US2021/039388
International Filing Date 28.06.2021
IPC
A61K 31/185 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A61K 33/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
06Aluminium, calcium or magnesium; Compounds thereof
A61K 33/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
06Aluminium, calcium or magnesium; Compounds thereof
08Oxides; Hydroxides
CPC
A61K 2800/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
52Stabilizers
522Antioxidants; Radical scavengers
A61K 8/062
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
06Emulsions
062Oil-in-water emulsions
A61K 8/498
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
4973with oxygen as the only hetero atom
498having 6-membered rings or their condensed derivatives, e.g. coumarin
A61K 8/676
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
67Vitamins
676Ascorbic acid, i.e. vitamin C
A61Q 19/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
A61Q 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
02for chemically bleaching or whitening the skin
Applicants
  • TOPIX PHARMACEUTICALS, INC. [US]/[US]
Inventors
  • HERNANDEZ, Steven, M.
Agents
  • D'ANTONIO, Alyssa, N.
  • PARADISO, Robert, J.
  • SIERCHIO, Daniel, D.
  • KESSLEN, Mark, L.
  • TOMA, David
Priority Data
63/045,40929.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TOPICAL VITAMIN C COMPOSITION
(FR) COMPOSITION DE VITAMINE C TOPIQUE
Abstract
(EN) Disclosed in certain embodiments herein is a topical composition that delivers advanced environmental protection to the skin, brightens the complexion of the skin, and/or delivers anti-aging benefits to the skin by treating ntrinsic and/or extrinsic factors associated with the appearance and health of the skin. The topical composition may be an emulsion of an aqueous phase and an oily phase, or other two-phase system, that includes an ascorbate component and an antioxidant system that includes green tea polyphenols. Also disclosed herein are methods of administering the topical compositions described herein for treating a skin of a subject for effects of radical induced damage, atmospheric aging, and as part of a variety of dermatological procedures.
(FR) Dans certains modes de réalisation, la présente invention concerne une composition topique qui fournit une protection environnementale avancée à la peau, illumine le teint de la peau, et/ou délivre des bénéfices anti-âge à la peau par traitement de facteurs intrinsèques et/ou extrinsèques associés à l'aspect et à la santé de la peau. La composition topique peut être une émulsion d'une phase aqueuse et d'une phase huileuse, ou d'un autre système à deux phases, qui comprend un composant ascorbate et un système antioxydant qui comprend des polyphénols de thé vert. L'invention concerne également des méthodes d'administration des compositions topiques décrites ici pour traiter la peau d'un sujet pour les effets de dommages induits par des radicaux, le vieillissement atmosphérique, et dans le cadre de diverses procédures dermatologiques.
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