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1. WO2022010386 - USE OF COFACTOR FO AND ANALOGUES THEREOF AS A BIOLUMINESCENCE REACTION COMPONENT

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Publication Number WO/2022/010386
Publication Date 13.01.2022
International Application No. PCT/RU2021/050207
International Filing Date 08.07.2021
IPC
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C12N 9/02 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02Oxidoreductases (1.), e.g. luciferase
C12Q 1/66 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
66involving luciferase
Applicants
  • ЯМПОЛЬСКИЙ, Илья Викторович YAMPOL'SKIY, Il'ya Viktorovich [RU]/[RU]
Inventors
  • ЯМПОЛЬСКИЙ, Илья Викторович YAMPOL'SKIY, Il'ya Viktorovich
Agents
  • КОТЛОВ, Дмитрий Владимирович KOTLOV, Dmitry Vladimirovich
Priority Data
202012266708.07.2020RU
Publication Language Russian (ru)
Filing Language Russian (RU)
Designated States
Title
(EN) USE OF COFACTOR FO AND ANALOGUES THEREOF AS A BIOLUMINESCENCE REACTION COMPONENT
(FR) UTILISATION DE COFACTEUR FO ET DE SES ANALOGUES
(RU) ПРИМЕНЕНИЕ КОФАКТОРА F O И ЕГО АНАЛОГОВ В КАЧЕСТВЕ КОМПОНЕНТА БИОЛЮМИНЕСЦЕНТНОЙ РЕАКЦИИ
Abstract
(EN) Components of bioluminescent systems are widely used reagents for a large number of assays, including diagnostic systems, quality control systems, drug trial systems and the like. The present group of inventions discloses components of the bioluminescent system of Henlea petushkovi and Henlea rodionovae (Henlea sp.) worms, in particular bioluminescence cofactor (activator) molecules. The present group of inventions further discloses a method for identifying luciferase in biological samples using bioluminescence cofactor (activator) molecules from Henlea petushkovi and Henlea rodionovae (Henlea sp.) worms, and a method for detecting bioluminescence in a biological sample.
(FR) L'invention concerne des composants de systèmes bioluminescents qui sont largement utilisés comme réactifs dans une pluralité d'analyses, y compris des systèmes de diagnostic, des systèmes de contrôle qualité, des systèmes de test de préparations médicamenteuses, etc. Ce groupe d'inventions décrit des composants de systèmes bioluminescents de ver Odontosyllis undecimdonta, notamment de luciférine et de pré-luciférine. Ce groupe d'inventions concerne en outre un procédé de révélation de luciférase dans des échantillons biologiques en utilisant la luciférine et la pré-luciférine du système bioluminescent du ver Odontosyllis undecimdonta, ainsi qu'un procédé de détection de bioluminescence dans un échantillon biologique.
(RU) Компоненты биолюминесцентных систем - широко используемые реагенты для множества анализов, включая диагностические системы, системы контроля качества, системы тестирования лекарственных препаратов и т.д. Настоящая группа изобретений раскрывает компоненты биолюминесцентной системы червей Henlea petushkovi и Henlea rodionovae (Henlea sp.), в частности молекул кофакторов (активаторов) биолюминесцентной реакции. Кроме того, настоящая группа изобретений раскрывает метод выявления люциферазы в биологических образцах с использованием молекул кофакторов (активаторов) биолюминесцентной реакции червей Henlea petushkovi и Henlea rodionovae (Henlea sp.), а также способ детекции биолюминесценции в биологическом образце.
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