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1. WO2022010352 - 5-HYDROXYINDOLE AND ANALOGS THEREOF AS STIMULANTS OF GUT MOTILITY

Publication Number WO/2022/010352
Publication Date 13.01.2022
International Application No. PCT/NL2021/050434
International Filing Date 09.07.2021
IPC
A61K 31/404 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
A61P 1/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
10Laxatives
Applicants
  • RIJKSUNIVERSITEIT GRONINGEN [NL]/[NL]
Inventors
  • EL AIDY, Sahar
  • WACLAWIKOVA, Barbora
Agents
  • WITMANS, H.A.
Priority Data
63/050,17610.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) 5-HYDROXYINDOLE AND ANALOGS THEREOF AS STIMULANTS OF GUT MOTILITY
(FR) 5-HYDROXYINDOLE ET SES ANALOGUES UTILISÉS COMME STIMULANTS DE LA MOTILITÉ INTESTINALE
Abstract
(EN) The invention relates to 5-hydroxyindole (5-HI) and analogs thereof, and to their medical use, such as the treatment of conditions associated with reduced gut motility. Provided is a method for the treatment of a condition associated with reduced gut motility, comprising administering to a subject in need thereof a pharmaceutically effective amount of 5-HI or an analog thereof having the capability to increase gut motility.
(FR) L'invention porte sur le 5-hydroxyindole (5-HI) et ses analogues, et sur leur utilisation médicale, telle que le traitement d'affections associées à une diminution de la motilité intestinale. L'invention concerne une méthode pour le traitement d'une affection associée à une diminution de la motilité intestinale, consistant à administrer à un patient qui en a besoin une quantité pharmaceutiquement efficace de 5-HI ou d'un de ses analogues présentant la capacité d'augmenter la motilité intestinale.
Latest bibliographic data on file with the International Bureau