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1. WO2022010142 - ANALYSIS METHOD AND KIT FOR DIAGNOSIS OF RECURRENT MISCARRIAGE USING, AS BIOMARKER, PGK1 OR GENE ENCODING SAME

Publication Number WO/2022/010142
Publication Date 13.01.2022
International Application No. PCT/KR2021/007992
International Filing Date 25.06.2021
IPC
G01N 33/68 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
C12Q 1/6883 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
G01N 2333/91225
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
90Enzymes; Proenzymes
91Transferases (2.)
912transferring phosphorus containing groups, e.g. kinases (2.7)
91205Phosphotransferases in general
91225with a carboxyl group as acceptor (2.7.2)
G01N 2800/36
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
36Gynecology or obstetrics
G01N 33/689
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
689related to pregnancy or the gonads
Applicants
  • 차의과학대학교 산학협력단 CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR]/[KR]
Inventors
  • 백광현 BAEK, Kwang-Hyun
  • 박홍범 PARK, Hong-Beom
  • 배창주 PEI, Chang-Zhu
Agents
  • 오국진 OH, Kook-Jin
Priority Data
10-2020-008352507.07.2020KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) ANALYSIS METHOD AND KIT FOR DIAGNOSIS OF RECURRENT MISCARRIAGE USING, AS BIOMARKER, PGK1 OR GENE ENCODING SAME
(FR) MÉTHODE D'ANALYSE ET KIT POUR LE DIAGNOSTIC DE FAUSSES COUCHES À RÉPÉTITION UTILISANT, EN TANT QUE BIOMARQUEUR, PGK1 OU UN GÈNE CODANT POUR CELUI-CI
(KO) 바이오마커로서 PGK1 또는 이를 코딩하는 유전자를 사용한 반복유산 진단을 위한 분석방법 및 키트
Abstract
(EN) The present invention provides an analysis method, comprising the step of measuring the expression level of PGK1, or the expression level of a gene encoding same, in a sample from a subject, in order to provide information required for diagnosis of recurrent miscarriage. In addition, the present invention provides a kit for diagnosis of recurrent miscarriage, comprising a molecule capable of measuring the expression level of PGK1 or the expression level of a gene encoding same.
(FR) La présente invention concerne une méthode d'analyse comprenant l'étape de mesure du niveau d'expression de PGK1 ou du niveau d'expression d'un gène codant ce dernier, dans un échantillon provenant d'une patiente, afin de fournir des informations nécessaires au diagnostic de fausses couches à répétition. De plus, la présente invention concerne un kit de diagnostic de fausses couches à répétition, comprenant une molécule capable de mesurer le niveau d'expression de PGK1 ou le niveau d'expression d'un gène codant celui-ci.
(KO) 본 발명은 반복유산 진단에 필요한 정보를 제공하기 위하여, 대상자의 시료 중 PGK1 단백질의 발현량 또는 이를 코딩하는 유전자의 발현량을 측정하는 단계를 포함하는 분석방법을 제공한다. 또한, 본 발명은 PGK1 단백질의 발현량 또는 이를 코딩하는 유전자의 발현량을 측정할 수 있는 분자를 포함하는 반복유산 진단용 키트를 제공한다.
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