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1. WO2022009992 - CYCLIC PEPTIDE, PEPTIDE COMPLEX, AND DRUG COMPOSITION CONTAINING SAID CYCLIC PEPTIDE AND/OR SAID PEPTIDE COMPLEX

Publication Number WO/2022/009992
Publication Date 13.01.2022
International Application No. PCT/JP2021/026039
International Filing Date 09.07.2021
IPC
C07K 7/50 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
A61K 38/08 2019.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61K 38/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61K 38/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides
A61K 38/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61P 25/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • 国立大学法人東京大学 THE UNIVERSITY OF TOKYO [JP]/[JP]
Inventors
  • 菅 裕明 SUGA, Hiroaki
  • ルミット マイニ RUMIT, Maini
Agents
  • 稲葉 良幸 INABA, Yoshiyuki
  • 大貫 敏史 ONUKI, Toshifumi
Priority Data
2020-11948810.07.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) CYCLIC PEPTIDE, PEPTIDE COMPLEX, AND DRUG COMPOSITION CONTAINING SAID CYCLIC PEPTIDE AND/OR SAID PEPTIDE COMPLEX
(FR) PEPTIDE CYCLIQUE, COMPLEXE PEPTIDIQUE ET COMPOSITION MÉDICAMENTEUSE CONTENANT LEDIT PEPTIDE CYCLIQUE ET/OU LEDIT COMPLEXE PEPTIDIQUE
(JA) 環状ペプチド、ペプチド複合体、並びに、当該環状ペプチド及び/又は当該ペプチド複合体を含む医薬組成物
Abstract
(EN) The present invention relates to a cyclic peptide that contains a structure represented by formula (1) (In formula (1), Xaa1 is a basic amino acid, Xaa2 is any amino acid, Xaa3 and Xaa4 are each independently a basic amino acid or an aromatic amino acid, and n1 is an integer from 0-10.) or a pharmacologically acceptable salt of the cyclic peptide.
(FR) La présente invention concerne un peptide cyclique qui contient une structure représentée par la formule (1) (dans la formule (1), Xaa1 représente un acide aminé basique, Xaa2 représente n'importe quel acide aminé, Xaa3 et Xaa4 représentent chacun indépendamment un acide aminé basique ou un acide aminé aromatique et n1 représente un nombre entier de 0 à 10) ou un sel pharmacologiquement acceptable du peptide cyclique.
(JA) 本発明は、下記式(1): (式(1)中、Xaaは、塩基性アミノ酸であり、Xaaは、任意のアミノ酸であり、Xaa、及びXaaは、各々独立に、塩基性アミノ酸、又は芳香族アミノ酸であり、n1は、0~10の整数を示す。)で表される構造を含む、環状ペプチド、又はその薬理学的に許容可能な塩に関する。
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