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1. WO2022009709 - OIL-IN-WATER EMULSION COMPOSITION

Publication Number WO/2022/009709
Publication Date 13.01.2022
International Application No. PCT/JP2021/024241
International Filing Date 25.06.2021
IPC
A61Q 19/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
A61K 9/107 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions
A61K 8/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
06Emulsions
A61K 8/39 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
39Derivatives containing from 2 to 10 oxyalkylene groups
A61K 8/63 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
63Steroids; Derivatives thereof
A61K 8/92 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products
Applicants
  • 株式会社 資生堂 SHISEIDO COMPANY, LTD. [JP]/[JP]
Inventors
  • 宮原 令二 MIYAHARA, Reiji
  • 藤巻 大樹 FUJIMAKI, Daiki
  • 重川 宏美 SHIGEKAWA, Hiromi
Agents
  • 青木 篤 AOKI, Atsushi
  • 三橋 真二 MITSUHASHI, Shinji
  • 渡辺 陽一 WATANABE, Yoichi
  • 中島 勝 NAKAJIMA, Masaru
  • 池田 達則 IKEDA, Tatsunori
  • 河原 肇 KAWAHARA, Hajime
Priority Data
2020-11855309.07.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) OIL-IN-WATER EMULSION COMPOSITION
(FR) COMPOSITION D'ÉMULSION HUILE DANS L'EAU
(JA) 水中油型乳化組成物
Abstract
(EN) Provided is an oil-in-water emulsion composition which is excellent in emulsifying stability and contains a drug agent that can be dissolved in both an oil phase and a water phase where the coalescence of oil drops tends to be induced. This oil-in-water emulsion composition includes an aqueous dispersion medium and oil droplets dispersed in this aqueous dispersion medium. The oil droplets include a drug agent, a surfactant, and an oil component; the drug component has a logP value of -0.7 to 4.0; and the surfactant includes specific three types of non-ionic surfactants and an anionic surfactant.
(FR) L'invention concerne une composition d'émulsion huile dans l'eau qui présente une excellente stabilité émulsifiante et contient un agent médicamenteux qui peut être dissous à la fois dans une phase huileuse et dans une phase aqueuse où la coalescence des gouttes d'huile a tendance à être induite. Cette composition d'émulsion huile dans l'eau comprend un milieu de dispersion aqueux et des gouttelettes d'huile dispersées dans ce milieu de dispersion aqueux. Les gouttelettes d'huile comprennent un agent médicamenteux, un tensioactif et un constituant huileux ; le constituant médicamenteux a une valeur logP de -0,7 à 4,0 ; et le tensioactif comprend trois types spécifiques de tensioactifs non ioniques et un tensioactif anionique.
(JA) 油滴の合一を誘発しやすい、油相と水相の両方に溶解する性質を有する薬剤を含む、乳化安定性に優れる水中油型乳化組成物を提供する。 本開示の水中油型乳化組成物は、水性分散媒と、この水性分散媒中に分散している油滴とを含み、油滴が、薬剤、界面活性剤、及び油分を含み、かつ、薬剤が、-0.7~4.0のLogP値を有し、界面活性剤が、特定の三種類の非イオン性界面活性剤と、アニオン性界面活性剤とを含む。
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