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1. WO2022009437 - CORONAVIRUS-INACTIVATING AGENT

Publication Number WO/2022/009437
Publication Date 13.01.2022
International Application No. PCT/JP2020/027783
International Filing Date 17.07.2020
IPC
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A01N 31/04 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
31Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
04Oxygen or sulfur attached to an aliphatic side chain of a carbocyclic ring system
A01N 31/08 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
31Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
08Oxygen or sulfur directly attached to an aromatic ring system
A61K 31/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
075Ethers or acetals
08acyclic, e.g. paraformaldehyde
A61K 31/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
095Sulfur, selenium or tellurium compounds, e.g. thiols
10Sulfides; Sulfoxides; Sulfones
Applicants
  • 花王株式会社 KAO CORPORATION [JP]/[JP]
  • 学校法人北里研究所 THE KITASATO INSTITUTE [JP]/[JP]
Inventors
  • 八城 勢造 YASHIRO, Seizou
  • 石田 悠記 ISHIDA, Yuki
  • 森本 拓也 MORIMOTO, Takuya
  • 片山 和彦 KATAYAMA, Kazuhiko
  • 芳賀 慧 HAGA, Kei
  • 戸高 玲子 TODAKA, Reiko
Agents
  • 特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE
Priority Data
PCT/JP2020/02675708.07.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) CORONAVIRUS-INACTIVATING AGENT
(FR) AGENT D'INACTIVATION DU CORONAVIRUS
(JA) コロナウイルス不活化剤
Abstract
(EN) Provided is a SARS-CoV-2-inactivating agent exhibiting an excellent SARS-CoV-2-inactivating effect. This SARS coronavirus-2-inactivating agent contains, as effective components, a linear alkylbenzenesulfonate, and at least one polyoxyethylene alkyl ether selected from among a polyoxyethylene alkyl ether, in which the number of carbon atoms in an alkyl group is 12 and the addition molar number of ethylene oxide is 7, and a polyoxyethylene alkyl ether, in which the number of carbon atoms in an alkyl group is 12 and the addition molar number of ethylene oxide is 8, wherein the concentration (X) of the linear alkylbenzenesulfonate is at least 12.5 ppm, the concentration (Y) of the polyoxyethylene alkyl ether is at least 4.0 ppm, and expression (1) is satisfied. Y≥5,000×X-1.5 (1)
(FR) L'invention fournit un agent d'inactivation du SARS-CoV-2 qui présente d'excellents effets d'inactivation du SARS-CoV-2. Plus précisément, l'invention concerne un agent d'inactivation du SARS coronavirus-2 ayant pour principes actifs : un benzènesulfonate d'alkyle à chaîne droite ; et au moins une sorte de polyoxyéthylène alkyle éther choisie parmi un polyoxyéthylène alkyle éther de nombre de moles d'oxyde d'éthylène additionnées égal à 7 et de 12 atomes de carbone dans un groupe alkyle, et un polyoxyéthylène alkyle éther de nombre de moles d'oxyde d'éthylène additionnées égal à 8 et de 12 atomes de carbone dans un groupe alkyle. La concentration (X) en benzènesulfonate d'alkyle à chaîne droite est supérieure ou égale à 12,5ppm, et la concentration (Y) en polyoxyéthylène alkyle éther est supérieure ou égale à 4,0ppm. Enfin, la formule (1) suivante est satisfaite. Y≧5000×X-1,5 (1)
(JA) 優れたSARS-CoV-2不活化効果を示すSARS-CoV-2不活化剤の提供。 直鎖アルキルベンゼンスルホン酸塩、並びにアルキル基の炭素数が12でエチレンオキサイド付加モル数が7であるポリオキシエチレンアルキルエーテル及びアルキル基の炭素数が12でエチレンオキサイド付加モル数が8であるポリオキシエチレンアルキルエーテルから選ばれる少なくとも1種のポリオキシエチレンアルキルエーテルを有効成分とするSARSコロナウイルス-2不活化剤であって、 前記直鎖アルキルベンゼンスルホン酸塩の濃度(X)が12.5ppm以上、 前記ポリオキシエチレンアルキルエーテルの濃度(Y)が4.0ppm以上であり、且つ次式(1)を満たすSARSコロナウイルス-2不活化剤。 Y≧5000×X-1.5 (1)
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