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1. WO2022008848 - METHOD FOR PREPARING A VACCINE COMPOSITION FROM LYOPHILISED ANTIGENS

Publication Number WO/2022/008848
Publication Date 13.01.2022
International Application No. PCT/FR2021/051270
International Filing Date 08.07.2021
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/108 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
108Escherichia; Klebsiella
Applicants
  • VAXINANO [FR]/[FR]
  • BETBEDER, Didier [FR]/[FR]
Inventors
  • BETBEDER, Didier
Agents
  • BREESE, Pierre
Priority Data
FR200733810.07.2020FR
Publication Language French (fr)
Filing Language French (FR)
Designated States
Title
(EN) METHOD FOR PREPARING A VACCINE COMPOSITION FROM LYOPHILISED ANTIGENS
(FR) PROCEDE DE PREPARATION D'UNE COMPOSITION VACCINALE A PARTIR D'ANTIGENES LYOPHILISES
Abstract
(EN) The invention relates to the field of extemporaneous preparation of vaccine compositions from lyophilised antigens. More specifically, the invention relates to the use of cationic nanoparticles to render the lyophilised antigens more soluble without adding a lyophilisation aid, with a view to extemporaneous use for administering a vaccine composition. In a particular embodiment, the invention allows a vaccine formulation to be prepared or one or more valencies to be added to a previously formulated vaccine composition.
(FR) L'invention se rapporte au domaine de la préparation extemporanée de composition vaccinale à partir d'antigènes lyophilisés. Plus particulièrement, l'invention concerne l'utilisation de nanoparticules cationiques pour solubiliser des antigènes lyophilisés sans ajout d'adjuvant de lyophilisation en vue d'une utilisation extemporanée pour l'administration d'une composition vaccinale. Dans un mode de réalisation particulier, il permet de préparer une formulation vaccinale ou d'ajouter une ou plusieurs valences à une composition vaccinale préalablement formulée.
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