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1. WO2022008646 - ANTIBODIES THAT BIND PSMA AND GAMMA-DELTA T CELL RECEPTORS

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Publication Number WO/2022/008646
Publication Date 13.01.2022
International Application No. PCT/EP2021/068960
International Filing Date 08.07.2021
IPC
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 47/68 2017.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/30 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
Applicants
  • LAVA THERAPEUTICS N.V. [NL]/[NL]
Inventors
  • ROOVERS, Robertus Cornelis
  • VAN DER VLIET, Johannes Jelle
  • KING, Lisa Anna
  • PARREN, Paul Willem Henri Ida
  • GUIMARAIS IGLESIAS, Victoria
  • LUTJE HULSIK, David
  • MACHIELSEN, Peter Alexander Gerardus Maria
Agents
  • NEDERLANDSCH OCTROOIBUREAU
Priority Data
20184800.908.07.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTIBODIES THAT BIND PSMA AND GAMMA-DELTA T CELL RECEPTORS
(FR) ANTICORPS SE LIANT AU PSMA ET AUX RÉCEPTEURS DES LYMPHOCYTES T GAMMA-DELTA
Abstract
(EN) The present invention relates to antibodies capable of binding human PSMA and capable of binding a human Vγ9Vδ2 T cell receptor. The invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.
(FR) La présente invention concerne des anticorps pouvant se lier au PSMA humain et pouvant se lier à un récepteur de lymphocytes T humains Vγ9Vδ2. L'invention concerne en outre des compositions pharmaceutiques comprenant les anticorps de l'invention et des utilisations des anticorps de l'invention pour un traitement médical.
Latest bibliographic data on file with the International Bureau
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