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1. WO2022008632 - METHOD OF INCREASING THE POPULATION OF COPROCOCCUS SPP. IN THE GUT MICROBIOME

Publication Number WO/2022/008632
Publication Date 13.01.2022
International Application No. PCT/EP2021/068934
International Filing Date 08.07.2021
IPC
A61K 31/593 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
59Compounds containing 9,10-seco-cyclopentahydro- phenanthrene ring systems
5939,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3
A61K 31/015 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
01Hydrocarbons
015carbocyclic
A61K 31/197 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
197the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
A61K 31/375 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
365Lactones
375Ascorbic acid, i.e. vitamin C; Salts thereof
A61K 31/525 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
525Isoalloxazines, e.g. riboflavins, vitamin B2
A61K 45/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants
  • DSM IP ASSETS B.V. [NL]/[NL]
Inventors
  • PHAM, Thanh-Van
  • REHMAN, Ateequr
  • SEIFERT, Nicole
  • STEINERT, Robert
  • SYBESMA, Wilbert
Agents
  • KURT, Manfred
Priority Data
20184915.509.07.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF INCREASING THE POPULATION OF COPROCOCCUS SPP. IN THE GUT MICROBIOME
(FR) MÉTHODE D'AUGMENTATION DE LA POPULATION DE COPROCOCCUS SPP. DANS LE MICROBIOME INTESTINAL
Abstract
(EN) The population of Coprococcus spp. bacteria in the gut microbiome is lower in people with various diseases. We have found that administration of vitamins / vitamin combinations such as : the combination of Vitamin B2 and C; Vitamin D3; beta-carotene, and Vitamin B5, when administered directly to the gut, so that it provides nourishment to the gut microbiome directly, can result in an increase of Coprococcus spp.
(FR) La population de bactéries Coprococcus spp. dans le microbiome intestinal est plus faible chez les personnes atteintes de diverses maladies. Nous avons découvert que l'administration de vitamines ou de combinaisons de vitamines telles que : la combinaison de vitamine B2 et de vitamine C ; la vitamine D3 ; le bêta-carotène et la vitamine B5, lorsqu'elles sont administrées directement dans l'intestin de façon à nourrir directement le microbiome intestinal, peut conduire à une augmentation de Coprococcus spp.
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