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1. WO2022008586 - COMPOSITIONS HAVING NEUROREGENERATIVE APPLICATIONS

Publication Number WO/2022/008586
Publication Date 13.01.2022
International Application No. PCT/EP2021/068800
International Filing Date 07.07.2021
IPC
A61K 31/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 38/17 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61K 38/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
18Growth factors; Growth regulators
A61K 38/22 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
A61K 38/40 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
40Transferrins, e.g. lactoferrins, ovotransferrins
A61P 25/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • GRIFOLS WORLDWIDE OPERATIONS LIMITED [IE]/[IE]
Inventors
  • BARNETT, Thomas
  • ROSS, David A.
Agents
  • DURAN-CORRETJER, S.L.P.
Priority Data
63/049,51608.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS HAVING NEUROREGENERATIVE APPLICATIONS
(FR) COMPOSITIONS AYANT DES APPLICATIONS NEURORÉGÉNÉRATIVES
Abstract
(EN) Disclosed herein are pharmaceutical compositions containing transferrin and, or lactoferrin for use in promoting and or inducing the generation new neural cells in a patient that has suffered a neurodegenerative event arising from at least one of a traumatic brain injury, a non-traumatic brain injury, a spinal cord injury, a peripheral nerve injury, or peripheral neuropathy. Ideally, the transferrin and/or lactoferrin have a low iron saturation.
(FR) L'invention divulgue des compositions pharmaceutiques contenant de la transferrine et, ou de la lactoferrine pour une utilisation dans la promotion et ou l'induction de la génération de nouvelles cellules neuronales chez un patient qui a souffert d'un événement neurodégénératif ayant eu lieu du fait d'au moins une lésion cérébrale traumatique, une lésion cérébrale non traumatique, une lésion de la moelle épinière, une lésion nerveuse périphérique ou une neuropathie périphérique. Idéalement, la transferrine et/ou la lactoferrine ont une faible saturation en fer.
Latest bibliographic data on file with the International Bureau