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1. WO2022007955 - ANTIBODY BINDING TO HEPATITIS B VIRUS SURFACE ANTIGEN AND APPLICATION OF ANTIBODY

Publication Number WO/2022/007955
Publication Date 13.01.2022
International Application No. PCT/CN2021/105523
International Filing Date 09.07.2021
IPC
C07K 16/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
C07K 16/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C12N 15/13 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
13Immunoglobulins
A61P 31/20 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Applicants
  • 北京凯因科技股份有限公司 BEIJING KAWIN TECHNOLOGY SHARE-HOLDING CO., LTD. [CN]/[CN]
Inventors
  • 许铮 XU, Zheng
  • 常红艳 CHANG, Hongyan
  • 李响 LI, Xiang
  • 宋瑞 SONG, Rui
  • 刘影 LIU, Ying
  • 李峰 LI, Feng
Agents
  • 北京彩和律师事务所 BEIJING CAI HE LAW FIRM
Priority Data
202010659026.209.07.2020CN
202010659828.310.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) ANTIBODY BINDING TO HEPATITIS B VIRUS SURFACE ANTIGEN AND APPLICATION OF ANTIBODY
(FR) ANTICORPS SE LIANT À L'ANTIGÈNE DE SURFACE DU VIRUS DE L'HÉPATITE B ET APPLICATION D'ANTICORPS
(ZH) 结合乙型肝炎病毒表面抗原的抗体及其应用
Abstract
(EN) Provided are an antibody or antigen-binding fragment thereof that specifically binds to hepatitis B virus surface antigen (HBsAg), a pharmaceutical composition containing the antibody or antigen-binding fragment, and use thereof. Further provided are a nucleic acid molecule encoding the antibody, a vector and a host cell containing the nucleic acid molecule, and a method for preparing the antibody.
(FR) L'invention concerne un anticorps ou un fragment de liaison à l'antigène de celui-ci qui se lie spécifiquement à l'antigène de surface du virus de l'hépatite B (HBsAg), une composition pharmaceutique contenant l'anticorps ou le fragment de liaison à l'antigène, et son utilisation. L'invention concerne en outre une molécule d'acide nucléique codant pour l'anticorps, un vecteur et une cellule hôte contenant la molécule d'acide nucléique, et un procédé de préparation de l'anticorps.
(ZH) 提供了一种与乙型肝炎病毒表面抗原(HBsAg)特异性结合的抗体或其抗原结合片段,包含该抗体或抗原结合片段的药物组合物及其用途。还提供了编码该抗体的核酸分子、包含该核酸分子的载体和宿主细胞,以及制备该抗体的方法。
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