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1. WO2022007783 - USE OF ACETAMIDE DERIVATIVE IN PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE

Publication Number WO/2022/007783
Publication Date 13.01.2022
International Application No. PCT/CN2021/104702
International Filing Date 06.07.2021
IPC
A61K 31/5377 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
53751,4-Oxazines, e.g. morpholine
5377not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/444 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
444containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/437 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
437the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61P 25/28 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • 中国人民解放军军事科学院军事医学研究院 ACADEMY OF MILITARY MEDICAL SCIENCES [CN]/[CN]
Inventors
  • 李云峰 LI, Yunfeng
  • 张黎明 ZHANG, Liming
  • 姚如梦 YAO, Rumeng
  • 杨日芳 YANG, Rifang
  • 代威 DAI, Wei
Agents
  • 中国贸促会专利商标事务所有限公司 CCPIT PATENT AND TRADEMARK LAW OFFICE
Priority Data
202010658043.409.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF ACETAMIDE DERIVATIVE IN PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE
(FR) UTILISATION D'UN DÉRIVÉ ACÉTAMIDE DANS LA PRÉVENTION ET LE TRAITEMENT DE LA MALADIE D'ALZHEIMER
(ZH) 乙酰胺衍生物在防治阿尔茨海默症中的应用
Abstract
(EN) The present invention relates to the use of an acetamide derivative in the prevention and treatment of Alzheimer's disease (AD). In particular, the present invention relates to the use of a compound as represented by formula(I), and a solvate or a pharmaceutically acceptable salt thereof in the preparation of a drug for the prevention and/or treatment and/or adjunctive treatment of AD.
(FR) La présente invention concerne l'utilisation d'un dérivé acétamide dans la prévention et le traitement de la maladie d'Alzheimer (MA). En particulier, la présente invention concerne l'utilisation d'un composé tel que représenté par la formule (I), et un solvate ou un sel pharmaceutiquement acceptable de celui-ci dans la préparation d'un médicament pour la prévention et/ou le traitement et/ou le traitement d'appoint de la maladie d'Alzheimer.
(ZH) 涉及乙酰胺衍生物在防治阿尔茨海默症中的应用。具体涉及式(I)所示的化合物、其溶剂合物或可药用盐在制备预防和/或治疗和/或辅助治疗AD的药物中的用途,
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