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1. WO2022007745 - USE OF CHIAURANIB AND DRUG COMBINATION THEREOF IN TREATMENT OF NON-HODGKIN'S LYMPHOMA

Publication Number WO/2022/007745
Publication Date 13.01.2022
International Application No. PCT/CN2021/104503
International Filing Date 05.07.2021
IPC
A61K 31/47 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
A61K 31/4406 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4406only substituted in position 3, e.g. zimeldine
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • 深圳微芯生物科技股份有限公司 SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. [CN]/[CN]
  • 成都微芯药业有限公司 CHENGDU CHIPSCREEN PHARMACEUTICAL LTD. [CN]/[CN]
Inventors
  • 鲁先平 LU, Xianping
  • 宁志强 NING, Zhiqiang
  • 朱军 ZHU, Jun
  • 王晓宁 WANG, Xiaoning
Priority Data
202010654215.008.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF CHIAURANIB AND DRUG COMBINATION THEREOF IN TREATMENT OF NON-HODGKIN'S LYMPHOMA
(FR) UTILISATION DE CHIAURANIB ET D'UNE COMBINAISON MÉDICAMENTEUSE LE COMPRENANT DANS LE TRAITEMENT D'UN LYMPHOME NON HODGKINIEN
(ZH) 西奥罗尼及其联合用药治疗非霍奇金淋巴瘤的用途
Abstract
(EN) Provided are the use of chiauranib or a derivative thereof in the preparation of a drug for preventing and/or treating Non-Hodgkin's lymphoma, the use of a pharmaceutical composition containing chiauranib or the derivative thereof and chidamide or a derivative thereof in the preparation of a drug for preventing and/or treating Non-Hodgkin's lymphoma, and a drug combination composition. The chiauranib and the drug combination composition can effectively prevent and/or treat non-Hodgkin's lymphoma, particularly with higher effectiveness and safety within a particular amount range.
(FR) L'invention concerne l'utilisation de chiauranib ou d'un dérivé de celui-ci dans la préparation d'un médicament pour la prévention et/ou le traitement d'un lymphome non hodgkinien, l'utilisation d'une composition pharmaceutique contenant du chiauranib ou son dérivé et de chidamide ou un dérivé de celui-ci dans la préparation d'un médicament pour la prévention et/ou le traitement d'un lymphome non hodgkinien, et une composition de combinaison médicamenteuse. Le chiauranib et la composition de combinaison de médicaments peuvent prévenir et/ou traiter efficacement un lymphome non hodgkinien, en particulier avec une efficacité et une sécurité supérieures dans une plage de quantités particulière.
(ZH) 提供西奥罗尼或其衍生物在制备用于预防和/或治疗非霍奇金淋巴瘤的药物中的用途、包含西奥罗尼或其衍生物和西达本胺或其衍生物的药物组合物在制备用于预防和/或治疗非霍奇金淋巴瘤的药物中的用途、以及联合用药组合物。所述的西奥罗尼以及联合用药组合物能够有效预防和/或治疗非霍奇金淋巴瘤,尤其在特定用量范围内具有较高的有效性和安全性。
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