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1. WO2022007659 - HETEROCYCLIC IMMUNOMODULATOR

Publication Number WO/2022/007659
Publication Date 13.01.2022
International Application No. PCT/CN2021/102873
International Filing Date 28.06.2021
IPC
C07D 403/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
14containing three or more hetero rings
C07D 401/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
C07D 487/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 31/4412 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4412having oxo groups directly attached to the heterocyclic ring
Applicants
  • 北京诺诚健华医药科技有限公司 BEIJING INNOCARE PHARMA TECH CO., LTD. [CN]/[CN]
Inventors
  • 陈向阳 CHEN, Xiangyang
  • 庞育成 PANG, Yucheng
Priority Data
202010633550.206.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) HETEROCYCLIC IMMUNOMODULATOR
(FR) IMMUNOMODULATEUR HÉTÉROCYCLIQUE
(ZH) 杂环类免疫调节剂
Abstract
(EN) The present invention relates to a heterocyclic compound as an immunomodulator, or a pharmaceutically acceptable salt thereof. Specifically, the present invention relates to a compound as represented by general formula (I) and a pharmaceutically acceptable salt thereof. The present invention also relates to a method for preparing the compound or the pharmaceutically acceptable salt thereof. The compound can be used for treating and/or preventing tumors, inflammations or immune diseases.
(FR) La présente invention concerne un composé hétérocyclique utilisé en tant qu'immunomodulateur, ou un sel pharmaceutiquement acceptable de celui-ci. Plus précisément, la présente invention concerne un composé tel que représenté par la formule générale (I) et un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne également un procédé de préparation du composé ou du sel pharmaceutiquement acceptable de celui-ci. Le composé peut être utilisé pour traiter et/ou prévenir des maladies tumorales, inflammatoires ou immunitaires.
(ZH) 涉及作为免疫调节剂的杂环类化合物或其可药用的盐。具体而言,涉及一种通式(I)所示的化合物及其可药用的盐。还涉及所述化合物或其可药用的盐的制备方法。化合物可用于治疗和/或预防肿瘤、炎症或免疫性疾病。
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