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1. WO2022007283 - KIT AND METHOD FOR DIAGNOSING DISEASE ASSOCIATED WITH ABNORMAL FAP EXPRESSION, AND COMPUTER READABLE STORAGE MEDIUM

Publication Number WO/2022/007283
Publication Date 13.01.2022
International Application No. PCT/CN2020/127378
International Filing Date 07.11.2020
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
G01N 33/00 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
Applicants
  • 深圳霁因生物医药转化研究院 SHENZHEN INTERNATIONAL INSTITUTE FOR BIOMEDICAL RESEARCH [CN]/[CN]
Inventors
  • 苏金 SU, Jin
  • 李军旗 LI, Junqi
  • 杨鹏辉 YANG, Penghui
  • 彭晓敏 PENG, Xiaomin
  • 边寰 BIAN, Huan
Agents
  • 广州文冠倪律知识产权代理事务所(普通合伙) WINGUAN PATENT AND TRADEMARK ATTORNEYS
Priority Data
PCT/CN2020/10076708.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) KIT AND METHOD FOR DIAGNOSING DISEASE ASSOCIATED WITH ABNORMAL FAP EXPRESSION, AND COMPUTER READABLE STORAGE MEDIUM
(FR) KIT ET MÉTHODE DE DIAGNOSTIC D'UNE MALADIE ASSOCIÉE À UNE EXPRESSION DE FAP ANORMALE, ET SUPPORT DE STOCKAGE LISIBLE PAR ORDINATEUR
(ZH) 用于诊断FAP表达异常相关疾病的试剂盒、方法及计算机可读存储介质
Abstract
(EN) Disclosed in the present invention is an application of a protein or a polypeptide, capable of being bound to a fibroblast activation protein (FAP) antibody, in preparation of a kit used for diagnosing a disease associated with abnormal FAP expression. The present invention uses the protein or the polypeptide capable of being bound to the FAP antibody to diagnose the disease associated with the abnormal FAP expression by detecting the presence of the FAP antibody. The present invention provides an more efficient and more convenient diagnosis method for the disease associated with the abnormal FAP expression.
(FR) La présente invention concerne une application d'une protéine ou d'un polypeptide, capable d'être lié à un anticorps de protéine d'activation des fibroblastes (FAP), dans la préparation d'un kit utilisé pour diagnostiquer une maladie associée à une expression de FAP anormale. La présente invention utilise la protéine ou le polypeptide capable d'être lié à l'anticorps de FAP pour diagnostiquer la maladie associée à l'expression de FAP anormale par détection de la présence de l'anticorps de FAP. La présente invention concerne une méthode de diagnostic plus efficace et plus commode pour la maladie associée à l'expression de FAP anormale.
(ZH) 本发明公开了能够与成纤维细胞激活蛋白(FAP)抗体结合的蛋白或多肽在制备用于诊断FAP异常表达相关疾病的试剂盒中的应用。利用能够与FAP抗体结合的蛋白或多肽,通过检测FAP自身抗体的存在来诊断FAP表达异常相关的疾病。本发明提供了更加高效、便捷的FAP异常表达相关疾病诊断方法。
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