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1. WO2022006596 - A SINGLE PATIENT CLASSIFIER FOR T1 HIGH GRADE BLADDER CANCER

Publication Number WO/2022/006596
Publication Date 06.01.2022
International Application No. PCT/US2021/070809
International Filing Date 30.06.2021
IPC
G16B 25/10 2019.1
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
25ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
10Gene or protein expression profiling; Expression-ratio estimation or normalisation
Applicants
  • NORTHWESTERN UNIVERSITY [US]/[US]
  • UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS [US]/[US]
  • DXIGE RESEARCH INC. [CA]/[CA]
Inventors
  • MEEKS, Joshua J.
  • ROBERTS, Andrew Gordon
  • DE REYNIES, Aurelien
  • GROENEVELD, Clarice
Agents
  • MCBRIDE, M. Scott
Priority Data
63/046,46730.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A SINGLE PATIENT CLASSIFIER FOR T1 HIGH GRADE BLADDER CANCER
(FR) CLASSIFICATEUR DE PATIENT UNIQUE POUR LE CANCER DE LA VESSIE DE HAUT DEGRÉ DE MALIGNITÉ T1
Abstract
(EN) Disclosed are methods and systems for diagnosing, staging, stratifying, prognosing, and/or treating bladder cancer. In particular, the invention relates to methods and systems for classifying Stage T1 bladder cancer. The disclosed methods may include generating an mRNA expression profile for a sample of Stage T1 bladder cancer and classifying the sample based on the expression profile.
(FR) Des méthodes et des systèmes de diagnostic, de stadification, de stratification, de pronostic et/ou de traitement du cancer de la vessie sont divulgués. En particulier, l'invention concerne des méthodes et des systèmes de classification du cancer de la vessie de stade T1. Les méthodes divulguées peuvent consister à générer un profil d'expression d'ARNm pour un échantillon du cancer de la vessie de stade T1 et à classer l'échantillon sur la base du profil d'expression.
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