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1. WO2022006470 - METHODS OF TREATMENT FOR A KIDNEY DISEASE

Publication Number WO/2022/006470
Publication Date 06.01.2022
International Application No. PCT/US2021/040204
International Filing Date 01.07.2021
IPC
A61K 38/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
06Tripeptides
A61K 38/07 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
07Tetrapeptides
C07K 5/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
08Tripeptides
CPC
A61K 31/47
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
A61K 9/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
Applicants
  • VANDERBILT UNIVERSITY [US]/[US]
Inventors
  • PULLEY, Jill, M.
  • SHIREY-RICE, Jana, K.
  • JEROME, Rebecca, N.
  • BILLINGS IV, Frederic, T.
  • ZALESKI, Nicole, M.
Agents
  • COWIE, Ashley, M.
  • HARTWIG, Gregory, J.
Priority Data
63/047,21701.07.2020US
63/048,62306.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF TREATMENT FOR A KIDNEY DISEASE
(FR) MÉTHODES DE TRAITEMENT D'UNE MALADIE RÉNALE
Abstract
(EN) Disclosed herein are methods for preventing, treating, or reducing the severity of a cardiac surgery-associated acute kidney injury and extracorporeal membrane oxygenation-associated acute kidney injury in a subject. The methods include administering to the subject a therapeutically effective amount of a leukotriene receptor antagonist compound.
(FR) Sont divulguées ici des méthodes de prévention, de traitement ou de réduction de la gravité d'une insuffisance rénale aiguë associée à une chirurgie cardiaque et d'une insuffisance rénale aiguë associée à une oxygénation par membrane extracorporelle chez un sujet. Les méthodes comprennent l'administration au sujet d'une quantité thérapeutiquement efficace d'un composé antagoniste des récepteurs des leucotriènes.
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