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1. WO2022006426 - TRACE ELEMENT COMPOSITIONS, METHODS OF MAKING AND USE

Publication Number WO/2022/006426
Publication Date 06.01.2022
International Application No. PCT/US2021/040135
International Filing Date 01.07.2021
IPC
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 47/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
02Inorganic compounds
Applicants
  • AMERICAN REGENT, INC. [US]/[US]
Inventors
  • ANYARAMBHATLA, Gopal
  • LAWRENCE, Richard
  • MARINKOVIC, Jasmina
Agents
  • SCHMIDT, William D.
  • LENNA, Leo, G.
  • BOYADJIAN, Livia
  • SORELL, Peter
  • ZARKOWSKY, Erik
Priority Data
63/047,70802.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TRACE ELEMENT COMPOSITIONS, METHODS OF MAKING AND USE
(FR) COMPOSITIONS D'OLIGO-ÉLÉMENTS, LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Abstract
(EN) Injectable compositions that can be added to parenteral nutrition are provided. In particular, a stable injectable composition is provided which includes water, and at least one of about 800 μg to about 4,000 μg of zinc, about 40 μg to about 400 μg of copper, from about 4 μg to about 90 μg of selenium, or from about 1 μg to about 80 μg of manganese per 1 mL of the injectable composition. Methods of preparing and using of the stable injectable composition are also provided.
(FR) L'invention concerne des compositions injectables qui peuvent être ajoutées à une nutrition parentérale. En particulier, l'invention concerne une composition injectable stable qui comprend de l'eau, et au moins un élément parmi environ 800 μg à environ 4 000 μg de zinc, environ 40 μg à environ 400 μg de cuivre, environ 4 μg à environ 90 μg de sélénium, ou environ 1 μg à environ 80 μg de manganèse pour 1 ml de composition injectable. La présente invention concerne également des procédés de préparation et d'utilisation de la composition injectable stable.
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