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1. WO2022006374 - INCRNA-REGULATED GENE EXPRESSION SYSTEM

Publication Number WO/2022/006374
Publication Date 06.01.2022
International Application No. PCT/US2021/040051
International Filing Date 01.07.2021
IPC
C12N 15/113 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C12N 15/81 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
80for fungi
81for yeasts
C12N 15/90 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
90Stable introduction of foreign DNA into chromosome
Applicants
  • MEMORIAL SLOAN KETTERING CANCER CENTER [US]/[US]
Inventors
  • GARG, Angad
Agents
  • EWING, James, F.
  • FERNANDES, Jolene, S.
Priority Data
63/047,62802.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) INCRNA-REGULATED GENE EXPRESSION SYSTEM
(FR) SYSTÈME D'EXPRESSION GÉNIQUE RÉGULÉ PAR UN ARNINC
Abstract
(EN) The present disclosure provides gene expression systems and methods for producing and/or overexpressing heterologous polypeptides in eukaryotic cells. Kits for practicing the methods are also disclosed.
(FR) La présente invention concerne des systèmes d'expression génique et des méthodes de production et/ou de surexpression de polypeptides hétérologues dans des cellules eucaryotes. L'invention concerne également des kits permettant de mettre en œuvre les méthodes.
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