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1. WO2022006238 - SOLID FORMS OF (Z)-METHYL 3-(((4-(N-METHYL-2-(4-METHYLPIPERAZIN-L- YL)ACETAMIDO)PHENYL)AMINO)(PHENYL)METHYLENE)-2-OXO-2, 3-DIHYDRO- LH-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLATE AND SALTS THEREOF

Publication Number WO/2022/006238
Publication Date 06.01.2022
International Application No. PCT/US2021/039838
International Filing Date 30.06.2021
IPC
A61K 31/437 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
437the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61K 31/496 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A61K 31/5377 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
53751,4-Oxazines, e.g. morpholine
5377not condensed and containing further heterocyclic rings, e.g. timolol
CPC
A61K 31/496
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
Applicants
  • ANGION BIOMEDICA CORP. [US]/[US]
Inventors
  • ANDERSEN, Marc W.
  • ABU-IZZA, Khawla Abdullah
Agents
  • D'AMATO, Erica M.
  • ADAMS, Melissa M.
  • ADATO, Ronen
  • BOUZA, Alexandra A.
  • BUTEAU, Kristen C.
  • BYCHOWSKI, Meaghan E.
  • DAUKSS, Dana M.
  • FLYNN, Peter A.
  • HAULBROOK, William R.
  • HERSCHBACH JARRELL, Brenda
  • KAUR, Mandeep
  • KITTO, Rebekah Z.
  • LI, Xiaodong
  • LYON, Charles E.
  • MA, Longle
  • MEDINA, Rolando
  • MONROE, Margo R.
  • PACE, Nicholas J.
  • POLIO, Samuel R.
  • REARICK, John P.
  • REESE, Brian E.
  • SCHMITT, Michael
  • SCHONEWALD, Stephanie L.
  • SHINALL, Michael A.
  • SHORE, David E.
  • SUBRAMANIAN, Sowmya
  • TSE, Janet M.
  • VETTER, Michael L.
  • VRABLIK, Tracy L.
Priority Data
63/046,91901.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SOLID FORMS OF (Z)-METHYL 3-(((4-(N-METHYL-2-(4-METHYLPIPERAZIN-L- YL)ACETAMIDO)PHENYL)AMINO)(PHENYL)METHYLENE)-2-OXO-2, 3-DIHYDRO- LH-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLATE AND SALTS THEREOF
(FR) FORMES SOLIDES DE (Z)-MÉTHYL 3-(((4-(N-MÉTHYL-2-(4-MÉTHYLPIPÉRAZIN-1-YL)ACÉTAMIDO)PHÉNYL)AMINO)(PHÉNYL)MÉTHYLÈNE)-2-OXO-2, 3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLATE ET DES SELS DE CELUI-CI
Abstract
(EN) The present disclosure provides crystalline solid forms of an antifibrotic agent, pharmaceutical compositions comprising the same, and methods of use thereof.
(FR) La présente invention concerne des formes solides cristallines d'un agent antifibrotique, des compositions pharmaceutiques les comprenant et des procédés d'utilisation de celles-ci.
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